Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
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Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
.

Sumario:

En el mundo de hoy se establece la importancia de identificar biomarcadores de toxicidad como una forma preventiva ante la presencia de diversos compuestos químicos contaminantes que actúan como agentes xenobióticos en diversos organismos, además de permitir la evaluación de la inocuidad alimentaria en diversas matrices por medio del desarrollo de nuevas metodologías exploratorias como la metabolómica y la xenometabolómica. De esta forma, el objetivo de esta revisión estriba en el análisis de la información reportada con respecto a la determinación de biomarcadores de toxicidad estudiados en plantas y diferentes productos alimentarios, además del análisis de las diferentes aplicaciones actuales de las ciencias ómicas para la determinación d... Ver más

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Biosalud

1657-9550

2462-960X

Betancourt Arango, Juan Pablo

Patiño Ospina, Alejandro

Taborda Ocampo, Gonzalo

Fiscal Ladino, Jhon Alexander

UNIVERSIDAD DE CALDAS

10.17151/biosa.2020.19.1.1

19

2025-02-05

7

30

Colombia

contaminantes emergentes

ciencias ómicas

biomarcadores de toxicidad

xenometabolómica

http://purl.org/coar/access_right/c_abf2

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spelling Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
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Biosalud
En el mundo de hoy se establece la importancia de identificar biomarcadores de toxicidad como una forma preventiva ante la presencia de diversos compuestos químicos contaminantes que actúan como agentes xenobióticos en diversos organismos, además de permitir la evaluación de la inocuidad alimentaria en diversas matrices por medio del desarrollo de nuevas metodologías exploratorias como la metabolómica y la xenometabolómica. De esta forma, el objetivo de esta revisión estriba en el análisis de la información reportada con respecto a la determinación de biomarcadores de toxicidad estudiados en plantas y diferentes productos alimentarios, además del análisis de las diferentes aplicaciones actuales de las ciencias ómicas para la determinación de metabolitos respuesta. Finalmente, se busca comprender la aplicación de la metabolómica y la xenometabolómica frente a la identificación de biomarcadores de toxicidad en el medio ambiente y en los alimentos, ante la presencia de agentes contaminantes actuales como plaguicidas, metales pesados, plásticos y microplásticos, que permiten ver la importancia de estas ciencias en la identificación de biomarcadores mediante el desarrollo de las ómicas.
https://creativecommons.org/licenses/by-nc-sa/4.0/
Español
Betancourt Arango, Juan Pablo
Dong, H., Yan, G. L., Han, Y., Sun, H., Zhang, A. H., Li, X. N., & Wang, X. J. (2015). UPLC-Q-TOF/MS-based metabolomic studies on the toxicity mechanisms of traditional Chinese medicine Chuanwu and the detoxification mechanisms of Gancao, Baishao, and Ganjiang. Chinese Journal of Natural Medicines, 13(9), 687–698. https://doi.org/10.1016/S1875-5364(15)30067-4
https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/9851
Patiño Ospina, Alejandro
Taborda Ocampo, Gonzalo
Universidad de Caldas
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Fiscal Ladino, Jhon Alexander
contaminantes emergentes
ciencias ómicas
biomarcadores de toxicidad
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In today’s world lies the importance of identifying biomarkers of toxicity as a preventive way in the presence of various chemical contaminants that act as xenobiotic agents in various organiss, in addition to allowing the evaluation of food safety in various matrices, through the development of new exploratory methodologies such as metabolomics and xenometabolomics. In this way, the objective of this review lies in the analysis in relation to the information reported towards the determination of toxicity biomarkers studied in plants and different food products, in addition to the analysis of the different current applications of omics sciences for the determination of response metabolites. Finally, it seeks to understand the application of metabolomics and xenometabolomics to the identification of biomarkers of toxicity in the environment and in food, in the presence of current pollutants such as pesticides, heavy metals, plastics and microplastics, which allow us to see the importance of these sciences in the identification of biomarkers through the development of omics.
emerging contaminants
Applications of xenometabolomics for the identification of biomarkers of toxicity: a review of the topic
omic sciences
toxicity biomarkers
xenometabolomics
Journal article
https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/download/9851/7756
2025-02-05T00:00:00Z
2025-02-05T00:00:00Z
2025-02-05
1657-9550
2462-960X
https://doi.org/10.17151/biosa.2020.19.1.1
7
30
10.17151/biosa.2020.19.1.1
institution UNIVERSIDAD DE CALDAS
thumbnail https://nuevo.metarevistas.org/UNIVERSIDADDECALDAS/logo.png
country_str Colombia
collection Biosalud
title Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
spellingShingle Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
Betancourt Arango, Juan Pablo
Patiño Ospina, Alejandro
Taborda Ocampo, Gonzalo
Fiscal Ladino, Jhon Alexander
contaminantes emergentes
ciencias ómicas
biomarcadores de toxicidad
xenometabolómica
emerging contaminants
omic sciences
toxicity biomarkers
xenometabolomics
title_short Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
title_full Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
title_fullStr Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
title_full_unstemmed Aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
title_sort aplicaciones de la xenometabolómica para la identificación de biomarcadores de toxicidad: una revisión del tema
title_eng Applications of xenometabolomics for the identification of biomarkers of toxicity: a review of the topic
description En el mundo de hoy se establece la importancia de identificar biomarcadores de toxicidad como una forma preventiva ante la presencia de diversos compuestos químicos contaminantes que actúan como agentes xenobióticos en diversos organismos, además de permitir la evaluación de la inocuidad alimentaria en diversas matrices por medio del desarrollo de nuevas metodologías exploratorias como la metabolómica y la xenometabolómica. De esta forma, el objetivo de esta revisión estriba en el análisis de la información reportada con respecto a la determinación de biomarcadores de toxicidad estudiados en plantas y diferentes productos alimentarios, además del análisis de las diferentes aplicaciones actuales de las ciencias ómicas para la determinación de metabolitos respuesta. Finalmente, se busca comprender la aplicación de la metabolómica y la xenometabolómica frente a la identificación de biomarcadores de toxicidad en el medio ambiente y en los alimentos, ante la presencia de agentes contaminantes actuales como plaguicidas, metales pesados, plásticos y microplásticos, que permiten ver la importancia de estas ciencias en la identificación de biomarcadores mediante el desarrollo de las ómicas.
description_eng In today’s world lies the importance of identifying biomarkers of toxicity as a preventive way in the presence of various chemical contaminants that act as xenobiotic agents in various organiss, in addition to allowing the evaluation of food safety in various matrices, through the development of new exploratory methodologies such as metabolomics and xenometabolomics. In this way, the objective of this review lies in the analysis in relation to the information reported towards the determination of toxicity biomarkers studied in plants and different food products, in addition to the analysis of the different current applications of omics sciences for the determination of response metabolites. Finally, it seeks to understand the application of metabolomics and xenometabolomics to the identification of biomarkers of toxicity in the environment and in food, in the presence of current pollutants such as pesticides, heavy metals, plastics and microplastics, which allow us to see the importance of these sciences in the identification of biomarkers through the development of omics.
author Betancourt Arango, Juan Pablo
Patiño Ospina, Alejandro
Taborda Ocampo, Gonzalo
Fiscal Ladino, Jhon Alexander
author_facet Betancourt Arango, Juan Pablo
Patiño Ospina, Alejandro
Taborda Ocampo, Gonzalo
Fiscal Ladino, Jhon Alexander
topicspa_str_mv contaminantes emergentes
ciencias ómicas
biomarcadores de toxicidad
xenometabolómica
topic contaminantes emergentes
ciencias ómicas
biomarcadores de toxicidad
xenometabolómica
emerging contaminants
omic sciences
toxicity biomarkers
xenometabolomics
topic_facet contaminantes emergentes
ciencias ómicas
biomarcadores de toxicidad
xenometabolómica
emerging contaminants
omic sciences
toxicity biomarkers
xenometabolomics
citationvolume 19
citationissue 1
citationedition Núm. 1 , Año 2020 : Enero-Junio
publisher Universidad de Caldas
ispartofjournal Biosalud
source https://revistasojs.ucaldas.edu.co/index.php/biosalud/article/view/9851
language Español
format Article
rights http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/4.0/
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