Funcionamiento normal y aumentado de la glándula tiroides en equinos
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Objetivo: Describir y analizar el funcionamiento normal de la glándula tiroides en equinos y los factores que aumentan en ellos los niveles de hormonas tiroideas. Materiales y métodos: Mediante la revisión de la literatura disponible de los últimos 50 años en las bases de datos BBCS-LILACS, fuente académica, IB-PsycINFO, IBSSCI, IB-SciELO, Scopus y Scirus, al igual que artículos históricos, textos y referencias citadas en trabajos publicados. Resultados: la información obtenida relacionada con los objetivos propuestos en la presente revisión, permite clasificar en 4 secciones a saber: síntesis y secr... Ver más
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info:eu-repo/semantics/openAccess
Luna Azul - 2015
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Funcionamiento normal y aumentado de la glándula tiroides en equinos Hubert, J.D.; Beadle, R.E.; Norwood, G. (2002). Equine anhidrosis. Vet Clin Equine 18 (2): 355–369. Malinowski, K.; Christensen, H.D. (1996). Hafs and Scanes C.G. Age and breed differences in thyroid hormones, insulin-like growth factor (IGF)-I and IGF binding proteins in female horses. J Anim Sci. 74: 1936-1942. Lucke, V.M. (1984). Lane JG.C-cell tumours of the thyroid in the horse. Eq Vet J. 16 (1):28–30. Kratzsch, J.; Pulzer, F. (2008). Thyroid gland development and defects. Best Pract Res Clin Endocrinol Metab. 22 (1): 57–75. Johnson, P.J.; Messer, N.T.; Slight, H.S.; Wiedmeyer, C.; Buff, P.; Ganjam. V.K. (2004). Endocrinopathic Laminitis in the Horse. Vet Clin Equine. 3 (1): 45-56. Johnson, C.A. (2002). Thyroid Issues in Reproduction. Clin Tech Small Anim Pract. 17 (3): 129-132. Hyypp, S. (2005). Endocrinal responses in exercising horses. Livestock Production Science 92: 113–121. Hurcombe, S.D. (2011). Hypothalamic-Pituitary gland axis function and disfunction in horses. Vet Clin Equine. 27: 1– 17. Hulbert, A.J. (2000). Thyroid hormones and their effects: a new perspective. Biol. Rev. 75:519-631. Gray, H. (2000). Anatomy of the human body. 20va (ed.) New York: Bartleby Gϋrbϋz, B.L.; Yalti, S.; Ficicioglu, C.; Tas, S. (2005). The relation of serum and follicular fluid leptin and ovarian steroid levels in response to induction of ovulation in in vitro fertilization cycles. Eur J Obstet Gynecol Reprod Biol 118: 214–218. Medica, P.; Cravana, C.; Fazio, E. D.V.M.; Ferlazzo, A. (2011). 24-hour endocrine profiles of quarter horses under resting conditions. Equine Vet J. 31: 35-40. Glover, C.M.; Miller, L.M.; Dybdal, N.O.; Lopez, A. Duckett W.M.; McFarlane, D. (2009). Extrapituitary and Pituitary Pathological Findings in Horses with Pituitary Pars Intermedia Dysfunction: A Retrospective Study. Equine Vet J. 29 (39). Gerlach, T.; Aurich, J.E. (2000). Regulation of seasonal reproductive activity in the stallion, ram and hamster. Anim Reprod Sci. 58:197–213. Geor, R.J. (2010). Nutrition and Exercise in the Management of Horses and Ponies at High Risk for Laminitis. Equine Vet J. 30 (9): 463-470. Geor, R.J. (2008). Metabolic Predispositions to Laminitis in Horses and Ponies: Obesity, Insulin Resistance and Metabolic Syndromes. Equine Vet J. 28 (12): 753-759. Ge´rard, N.; Duchamp, G.; Magistrini, M. (1999). Relationships between follicular fluid composition and follicular /oocyte quality in the mare. Livestock Production Science 60:243–253. Frank, N. (2009). Equine Metabolic Syndrome. Vet Clin North Am Equine Pract. 29(5): 239-255. Frank, N.; Sojka, J.; Messer, N.T.(2002) Equine thyroid dysfunction. Vet Clin Equine 18: 305–319. Fitzgerald, B.P.; Davison, L.A. (1998). Thyroxine concentrations are elevated in mares which continue to exhibit estrous cycles during the nonbreeding season. Equine Vet J. 18 (1):48-51. McDermott, M.T.; Ridgway, C.E.(1998). Central hyperthyroidism. Endocrinol Metab Clin North Am. 27 (1): 187-203. Messer, N.T.; Riddle, T.; Traub-Dargatz J.L.; Dargatz, D.A.; Refsal, K.J.; Thompson, D.L. (1998). Thyroid Hormone Levels in Thoroughbred Mares and Their Foals at Parturition. Proceedings of the Annual Convention of the AAEP. 44: 248-251. Fazio, E; Medica, P.; Cravana, C.; Messineo, C.; Ferlazzo, A. (2007) Total and free iodothyronine levels of growing Thoroughbred foals: Effects of weaning and gender. Livestock Science. 110 (3): 207–213. Walsh, D.N.; McGowan, C.M.; McGowan, T.; Lamb, S.V.; Schanbacher, B.J.Place, N.J. (2009). Correlation of Plasma Insulin Concentration with Laminitis Score in a Field Study of Equine Cushing’s Disease and Equine Metabolic Syndrome. Equine Vet J. 29 (2): 87-94. Text http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:eu-repo/semantics/article Warner, M.H.; Beckett, G.J. (2010). Mechanisms behind the non-thyroidal illness syndrome: an update. J Endocrinol. 205:1–13. Intern Med 12: 475–7. Ueki, H.; Kowatari, Y.; Oyamada, T.; Oikawa, M.; Yoshikawa, H. (2004). Non-functional C-cell Adenoma in Aged Horses. J Comp Pathol 131(2-3):157–165. Nagy, P.; Guillaume, D.; Daels, P. (2000). Seasonality in mares. Anim Reprod Sci 60: 245–262. Toribio, R.E. (2011). Endocrine Dysregulation in Critically I l l Foals and Horses. Vet Clin North Am Equine Pract. 27 (1):35-47. Toribio, R.E.; Duckett, W.M. (2004). Equine Internal Medicine 2da ed. Estados Unidos de América: Saunders. pp. 1342-1355. Tahboub, R.; Arafah, B.M. (2009). Sex steroids and the thyroid. Best Pract Res Clin Endocrinol Metab. 23 (6): 769– 780. Slebodzi´nski. Ovarian iodide uptake and triiodothyronine generation in follicular fluid the enigma of the thyroid ovary interaction. Domestic Animal Endocrinol (2005). 29: 97– 103. Sisson, S.; Grossman, J.D. (2000). Anatomía de los animales domésticos. 5a ed. Barcelona: Manson. S.A. pp.173-176. Rudi’s, P.; R´onai, Z.; Bartha, T. (2005). Thyroid hormone metabolism in the brain of domestic animals. Domest Anim Endocrinol. 29: 88–96. Ramirez, S.; McClure, J.J.; Moore, R.M.; Wolfsheimer, K.J.; Gaunt, S.D.; Mirza M.H. et al (2010). Hyperthyroidism associated with a thyroid adenocarcinoma in a 21-year-old gelding. J Vet Roser, J.F. (2008). Regulation of esticular function in the stallion: An intricate network of endocrine, paracrine and autocrine systems. Anim eprod Sci. 107:179–196. Petersen, A.D.; Schott, C.H. (2005) Cutaneous Markers of Disorders Affecting Adult Horses. Vet Clin North Am Equine Pract. 4 (4):324-338. Nicassio, M.; Aiudi, G.; Silvestre, F.; Matarrese, R.; De Sandro, A.S.; Lacalandra, G.M. (2008). Free thyroid hormone and cortisol levels in stallions during the breeding season. J Anim Sci. 107(3-4): 335-336. Fazio, E.; Medica, P.; Cravana, C.; Messineo, C.; Ferlazzo, A. (2007). Total and free iodothyronine levels of growing Thoroughbred foals: Effects of weaning and gender. Department of Morphology, Biochemistry, Physiology and Animal Productions. Livestock Science. 110 (3): 207–213. Durham, A. (2010). The Pharmacologic Basis for the Treatment of Endocrinopathic Laminitis. Vet Clin North Am Equine Pract. 26 (1): 115-128. Doige, C.E.; McLaughlin, B.G. (1981). Hyperplastic Goitre in Newborn Foals in Western Canada. Can. vet. J. 22: 42- 45. Luna Azul - 2015 Objetivo: Describir y analizar el funcionamiento normal de la glándula tiroides en equinos y los factores que aumentan en ellos los niveles de hormonas tiroideas. Materiales y métodos: Mediante la revisión de la literatura disponible de los últimos 50 años en las bases de datos BBCS-LILACS, fuente académica, IB-PsycINFO, IBSSCI, IB-SciELO, Scopus y Scirus, al igual que artículos históricos, textos y referencias citadas en trabajos publicados. Resultados: la información obtenida relacionada con los objetivos propuestos en la presente revisión, permite clasificar en 4 secciones a saber: síntesis y secreción de hormonas tiroideas; transporte y metabolismo; funciones; hipertiroidismo en los equinos. Conclusión: La glándula tiroides juega un papel importante, como productora de hormonas tiroideas, las cuales son necesarias para la diferenciación celular y crecimiento del organismo. El buen funcionamiento de las vías metabólicas depende de estas hormonas, las que tienen efectos específicos sobre diferentes órganos, manteniendo la homeostasis en todos los tejidos.  Osorio, Jóse Henry Equinos hormona tiroidea metabolismo 35 Núm. 35 , Año 2012 : Julio - Diciembre Artículo de revista application/pdf Universidad de Caldas Luna Azul Español https://creativecommons.org/licenses/by-nc-sa/4.0/ https://revistasojs.ucaldas.edu.co/index.php/lunazul/article/view/1736 Abraham, G.; Allersmeier, M.; Schusser, G.F.; Ungemach, F. R. (2011). Serum thyroid hormone, insulin, glucose, triglycerides and protein concentrations in normal horses: Association with topical dexamethasone usage. Vet J; 188: 307–312. Blomme, E.A.; Sugimoto, Y.; Lin Y.C.; Capen, C.C.; Rosol, T.J. (1999). Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts. Mol Cell Endocrinol. 152:189– 197. Divers, J.T. (2008). Endocrine Testing in Horses: Metabolic Syndrome and Cushing’s Disease. Equine Vet J. 28 (5): 315-316. Dittrich, R.; Beckmann, M.W.; Oppelt, P.G.; Hoffmann, I; Lotz, L; Kuwert, T et al. (2011) Thyroid hormone receptors and reproduction. J Reprod Immunol. 90:58–66. Crockford, S.J. (2003). Thyroid rhythm phenotypes and hominid evolution: a new paradigm implicates pulsatile hormone secretion in speciation and adaptation changes. Comp Biochem Physiol AMol Integr Physiol. 135: 105–129. Clutterbuck, A.L.; Harris, P.; Allaway, D.; Mobasheri, A; (2010). Matrix metalloproteinases in inflammatory pathologies of the horse. Vet J. 183: 27–38. Cianchetta, S.; Bernardo, J.; Romeo, G.; Rhoden, K.J. (2010). Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L. Toxicol Appl harmacol. 243: 372–380. Christensen, R.A.; Malinowski, K.; Massenzio, A.M.; Hafs, H.D.; Scanes, C.G. (1997). Acute effects of short-term feed deprivation and refeeding on circulating concentrations of metabolites, insulin-like growth factor i, insulin-like growth factor binding proteins, somatotropin, and thyroid hormones in adult geldings. J Anim Sci. 75:1351-1358. Buff, P.R.; Messer, N.T.; Cogswell, A.M.; Johnson, P.J.; Keisler, D.H.; Ganjama V.K. (2007) Seasonal and pulsatile dynamics of thyrotropin and leptin in mares maintained under a constant energy balance. Domestic Animal Endocrinol. 33: 430–436. Breuhaus, B.A. (2011). Disorders of the Equine Thyroid Gland. Vet Clin North Am Equine Pract. 27 (1):115-128. Publication Beck-Peccoz, P.; Persani, L.; Mannavola, D.; Campi, I. (2009). TSH-secreting adenomas. Best Pract Res Clin Endocrinol Metab. 23: 597-606. Ahmed, O.M.; El-Gareib, A.W.; El-bakry, A.M.; Abd ElTawab, S.M.; Ahmed R.G. (2008). Thyroid hormones states and brain development interactions. Int. J. Devl Neuroscience 26:147–209. Alberts, M.K.; McCann, J.P.; Woods, P.R. (2001) Hemithyroidectomy in a horse with confirmed hyperthyroidism. J Am Vet Med Assoc 217 (7):1051–4. Baragli, P.; Sgorbini, M.; Casini, L.; Ducci M.; Sighieri C. (2011). Early evidence of the anticipatory response of plasma catecholamine in equine exercise. Equine Vet J. 31:85-88. Barsnick, R.J.; Toribio, R.E. (2011). Endocrinology of the equine neonate energy metabolism in health and critical illness. Vet Clin Equine. 27: 49–58. metabolism Abstract Objective: to describe and analyze the normal functioning of the thyroid gland in equines and the factors which increase the thyroid hormone levels. Materials and methods: information from the last 50 years included in the BBCS-LILACS, Fuente Académica, IB-PsycINFO, IB-SSCI, IB-SciELO, Scopus and Scirus, data bases as well as historical articles, texts and references cited in work published to date were analyzed. Results: important information related to the objectives Luna Azul ISSN 1909-2474 No. 35, julio - diciembre 2012 ©Universidad de Caldas 321 proposed in the present review was found and analyzed. It was then divided into two sections as follow: synthesis, liberation and metabolism of thyroid hormones; factors that modify the thyroid hormone levels. Conclusion: the thyroid gland plays an important role producing thyroid hormones which are necessary for cellular differentiation and organic growth. The adequate functioning of metabolic ways depends on these hormones, which have specific effects on different organs maintaining homeostasis between all the tissues. Equines thyroid hormone Normal and increased functioning of the thyroid gland in horses Journal article 1909-2474 https://revistasojs.ucaldas.edu.co/index.php/lunazul/article/download/1736/1652 0122-5391 https://revistasojs.ucaldas.edu.co/index.php/lunazul/article/view/1736 337 2012-07-01T00:00:00Z 2012-07-01 321 2012-07-01T00:00:00Z |
institution |
UNIVERSIDAD DE CALDAS |
thumbnail |
https://nuevo.metarevistas.org/UNIVERSIDADDECALDAS/logo.png |
country_str |
Colombia |
collection |
Luna Azul |
title |
Funcionamiento normal y aumentado de la glándula tiroides en equinos |
spellingShingle |
Funcionamiento normal y aumentado de la glándula tiroides en equinos Osorio, Jóse Henry Equinos hormona tiroidea metabolismo metabolism Equines thyroid hormone |
title_short |
Funcionamiento normal y aumentado de la glándula tiroides en equinos |
title_full |
Funcionamiento normal y aumentado de la glándula tiroides en equinos |
title_fullStr |
Funcionamiento normal y aumentado de la glándula tiroides en equinos |
title_full_unstemmed |
Funcionamiento normal y aumentado de la glándula tiroides en equinos |
title_sort |
funcionamiento normal y aumentado de la glándula tiroides en equinos |
title_eng |
Normal and increased functioning of the thyroid gland in horses |
description |
Objetivo: Describir y analizar el funcionamiento normal de la glándula tiroides en equinos y los factores que aumentan en ellos los niveles de hormonas tiroideas. Materiales y métodos: Mediante la revisión de la literatura disponible de los últimos 50 años en las bases de datos BBCS-LILACS, fuente académica, IB-PsycINFO, IBSSCI, IB-SciELO, Scopus y Scirus, al igual que artículos históricos, textos y referencias citadas en trabajos publicados. Resultados: la información obtenida relacionada con los objetivos propuestos en la presente revisión, permite clasificar en 4 secciones a saber: síntesis y secreción de hormonas tiroideas; transporte y metabolismo; funciones; hipertiroidismo en los equinos. Conclusión: La glándula tiroides juega un papel importante, como productora de hormonas tiroideas, las cuales son necesarias para la diferenciación celular y crecimiento del organismo. El buen funcionamiento de las vías metabólicas depende de estas hormonas, las que tienen efectos específicos sobre diferentes órganos, manteniendo la homeostasis en todos los tejidos. 
|
description_eng |
Abstract
Objective: to describe and analyze the normal functioning of the thyroid gland in equines and the factors which increase the thyroid hormone levels. Materials and methods: information from the last 50 years included in the BBCS-LILACS, Fuente Académica, IB-PsycINFO, IB-SSCI, IB-SciELO, Scopus and Scirus, data bases as well as historical articles, texts and references cited in work published to date were analyzed. Results: important information related to the objectives Luna Azul ISSN 1909-2474 No. 35, julio - diciembre 2012 ©Universidad de Caldas 321 proposed in the present review was found and analyzed. It was then divided into two sections as follow: synthesis, liberation and metabolism of thyroid hormones; factors that modify the thyroid hormone levels. Conclusion: the thyroid gland plays an important role producing thyroid hormones which are necessary for cellular differentiation and organic growth. The adequate functioning of metabolic ways depends on these hormones, which have specific effects on different organs maintaining homeostasis between all the tissues.
|
author |
Osorio, Jóse Henry |
author_facet |
Osorio, Jóse Henry |
topicspa_str_mv |
Equinos hormona tiroidea metabolismo |
topic |
Equinos hormona tiroidea metabolismo metabolism Equines thyroid hormone |
topic_facet |
Equinos hormona tiroidea metabolismo metabolism Equines thyroid hormone |
citationissue |
35 |
citationedition |
Núm. 35 , Año 2012 : Julio - Diciembre |
publisher |
Universidad de Caldas |
ispartofjournal |
Luna Azul |
source |
https://revistasojs.ucaldas.edu.co/index.php/lunazul/article/view/1736 |
language |
Español |
format |
Article |
rights |
http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess Luna Azul - 2015 https://creativecommons.org/licenses/by-nc-sa/4.0/ |
references |
Hubert, J.D.; Beadle, R.E.; Norwood, G. (2002). Equine anhidrosis. Vet Clin Equine 18 (2): 355–369. Malinowski, K.; Christensen, H.D. (1996). Hafs and Scanes C.G. Age and breed differences in thyroid hormones, insulin-like growth factor (IGF)-I and IGF binding proteins in female horses. J Anim Sci. 74: 1936-1942. Lucke, V.M. (1984). Lane JG.C-cell tumours of the thyroid in the horse. Eq Vet J. 16 (1):28–30. Kratzsch, J.; Pulzer, F. (2008). Thyroid gland development and defects. Best Pract Res Clin Endocrinol Metab. 22 (1): 57–75. Johnson, P.J.; Messer, N.T.; Slight, H.S.; Wiedmeyer, C.; Buff, P.; Ganjam. V.K. (2004). Endocrinopathic Laminitis in the Horse. Vet Clin Equine. 3 (1): 45-56. Johnson, C.A. (2002). Thyroid Issues in Reproduction. Clin Tech Small Anim Pract. 17 (3): 129-132. Hyypp, S. (2005). Endocrinal responses in exercising horses. Livestock Production Science 92: 113–121. Hurcombe, S.D. (2011). Hypothalamic-Pituitary gland axis function and disfunction in horses. Vet Clin Equine. 27: 1– 17. Hulbert, A.J. (2000). Thyroid hormones and their effects: a new perspective. Biol. Rev. 75:519-631. Gray, H. (2000). Anatomy of the human body. 20va (ed.) New York: Bartleby Gϋrbϋz, B.L.; Yalti, S.; Ficicioglu, C.; Tas, S. (2005). The relation of serum and follicular fluid leptin and ovarian steroid levels in response to induction of ovulation in in vitro fertilization cycles. Eur J Obstet Gynecol Reprod Biol 118: 214–218. Medica, P.; Cravana, C.; Fazio, E. D.V.M.; Ferlazzo, A. (2011). 24-hour endocrine profiles of quarter horses under resting conditions. Equine Vet J. 31: 35-40. Glover, C.M.; Miller, L.M.; Dybdal, N.O.; Lopez, A. Duckett W.M.; McFarlane, D. (2009). Extrapituitary and Pituitary Pathological Findings in Horses with Pituitary Pars Intermedia Dysfunction: A Retrospective Study. Equine Vet J. 29 (39). Gerlach, T.; Aurich, J.E. (2000). Regulation of seasonal reproductive activity in the stallion, ram and hamster. Anim Reprod Sci. 58:197–213. Geor, R.J. (2010). Nutrition and Exercise in the Management of Horses and Ponies at High Risk for Laminitis. Equine Vet J. 30 (9): 463-470. Geor, R.J. (2008). Metabolic Predispositions to Laminitis in Horses and Ponies: Obesity, Insulin Resistance and Metabolic Syndromes. Equine Vet J. 28 (12): 753-759. Ge´rard, N.; Duchamp, G.; Magistrini, M. (1999). Relationships between follicular fluid composition and follicular /oocyte quality in the mare. Livestock Production Science 60:243–253. Frank, N. (2009). Equine Metabolic Syndrome. Vet Clin North Am Equine Pract. 29(5): 239-255. Frank, N.; Sojka, J.; Messer, N.T.(2002) Equine thyroid dysfunction. Vet Clin Equine 18: 305–319. Fitzgerald, B.P.; Davison, L.A. (1998). Thyroxine concentrations are elevated in mares which continue to exhibit estrous cycles during the nonbreeding season. Equine Vet J. 18 (1):48-51. McDermott, M.T.; Ridgway, C.E.(1998). Central hyperthyroidism. Endocrinol Metab Clin North Am. 27 (1): 187-203. Messer, N.T.; Riddle, T.; Traub-Dargatz J.L.; Dargatz, D.A.; Refsal, K.J.; Thompson, D.L. (1998). Thyroid Hormone Levels in Thoroughbred Mares and Their Foals at Parturition. Proceedings of the Annual Convention of the AAEP. 44: 248-251. Fazio, E; Medica, P.; Cravana, C.; Messineo, C.; Ferlazzo, A. (2007) Total and free iodothyronine levels of growing Thoroughbred foals: Effects of weaning and gender. Livestock Science. 110 (3): 207–213. Walsh, D.N.; McGowan, C.M.; McGowan, T.; Lamb, S.V.; Schanbacher, B.J.Place, N.J. (2009). Correlation of Plasma Insulin Concentration with Laminitis Score in a Field Study of Equine Cushing’s Disease and Equine Metabolic Syndrome. Equine Vet J. 29 (2): 87-94. Warner, M.H.; Beckett, G.J. (2010). Mechanisms behind the non-thyroidal illness syndrome: an update. J Endocrinol. 205:1–13. Intern Med 12: 475–7. Ueki, H.; Kowatari, Y.; Oyamada, T.; Oikawa, M.; Yoshikawa, H. (2004). Non-functional C-cell Adenoma in Aged Horses. J Comp Pathol 131(2-3):157–165. Nagy, P.; Guillaume, D.; Daels, P. (2000). Seasonality in mares. Anim Reprod Sci 60: 245–262. Toribio, R.E. (2011). Endocrine Dysregulation in Critically I l l Foals and Horses. Vet Clin North Am Equine Pract. 27 (1):35-47. Toribio, R.E.; Duckett, W.M. (2004). Equine Internal Medicine 2da ed. Estados Unidos de América: Saunders. pp. 1342-1355. Tahboub, R.; Arafah, B.M. (2009). Sex steroids and the thyroid. Best Pract Res Clin Endocrinol Metab. 23 (6): 769– 780. Slebodzi´nski. Ovarian iodide uptake and triiodothyronine generation in follicular fluid the enigma of the thyroid ovary interaction. Domestic Animal Endocrinol (2005). 29: 97– 103. Sisson, S.; Grossman, J.D. (2000). Anatomía de los animales domésticos. 5a ed. Barcelona: Manson. S.A. pp.173-176. Rudi’s, P.; R´onai, Z.; Bartha, T. (2005). Thyroid hormone metabolism in the brain of domestic animals. Domest Anim Endocrinol. 29: 88–96. Ramirez, S.; McClure, J.J.; Moore, R.M.; Wolfsheimer, K.J.; Gaunt, S.D.; Mirza M.H. et al (2010). Hyperthyroidism associated with a thyroid adenocarcinoma in a 21-year-old gelding. J Vet Roser, J.F. (2008). Regulation of esticular function in the stallion: An intricate network of endocrine, paracrine and autocrine systems. Anim eprod Sci. 107:179–196. Petersen, A.D.; Schott, C.H. (2005) Cutaneous Markers of Disorders Affecting Adult Horses. Vet Clin North Am Equine Pract. 4 (4):324-338. Nicassio, M.; Aiudi, G.; Silvestre, F.; Matarrese, R.; De Sandro, A.S.; Lacalandra, G.M. (2008). Free thyroid hormone and cortisol levels in stallions during the breeding season. J Anim Sci. 107(3-4): 335-336. Fazio, E.; Medica, P.; Cravana, C.; Messineo, C.; Ferlazzo, A. (2007). Total and free iodothyronine levels of growing Thoroughbred foals: Effects of weaning and gender. Department of Morphology, Biochemistry, Physiology and Animal Productions. Livestock Science. 110 (3): 207–213. Durham, A. (2010). The Pharmacologic Basis for the Treatment of Endocrinopathic Laminitis. Vet Clin North Am Equine Pract. 26 (1): 115-128. Doige, C.E.; McLaughlin, B.G. (1981). Hyperplastic Goitre in Newborn Foals in Western Canada. Can. vet. J. 22: 42- 45. Abraham, G.; Allersmeier, M.; Schusser, G.F.; Ungemach, F. R. (2011). Serum thyroid hormone, insulin, glucose, triglycerides and protein concentrations in normal horses: Association with topical dexamethasone usage. Vet J; 188: 307–312. Blomme, E.A.; Sugimoto, Y.; Lin Y.C.; Capen, C.C.; Rosol, T.J. (1999). Parathyroid hormone-related protein is a positive regulator of keratinocyte growth factor expression by normal dermal fibroblasts. Mol Cell Endocrinol. 152:189– 197. Divers, J.T. (2008). Endocrine Testing in Horses: Metabolic Syndrome and Cushing’s Disease. Equine Vet J. 28 (5): 315-316. Dittrich, R.; Beckmann, M.W.; Oppelt, P.G.; Hoffmann, I; Lotz, L; Kuwert, T et al. (2011) Thyroid hormone receptors and reproduction. J Reprod Immunol. 90:58–66. Crockford, S.J. (2003). Thyroid rhythm phenotypes and hominid evolution: a new paradigm implicates pulsatile hormone secretion in speciation and adaptation changes. Comp Biochem Physiol AMol Integr Physiol. 135: 105–129. Clutterbuck, A.L.; Harris, P.; Allaway, D.; Mobasheri, A; (2010). Matrix metalloproteinases in inflammatory pathologies of the horse. Vet J. 183: 27–38. Cianchetta, S.; Bernardo, J.; Romeo, G.; Rhoden, K.J. (2010). Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L. Toxicol Appl harmacol. 243: 372–380. Christensen, R.A.; Malinowski, K.; Massenzio, A.M.; Hafs, H.D.; Scanes, C.G. (1997). Acute effects of short-term feed deprivation and refeeding on circulating concentrations of metabolites, insulin-like growth factor i, insulin-like growth factor binding proteins, somatotropin, and thyroid hormones in adult geldings. J Anim Sci. 75:1351-1358. 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