Titulo:

Psychobiology and candidate endophenotypes in psychopathy
.

Guardado en:

2011-2084

2011-7922

4

2011-06-30

92

101

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International Journal of Psychological Research - 2011

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Psychobiology and candidate endophenotypes in psychopathy
Psychobiology and candidate endophenotypes in psychopathy
International Journal of Psychological Research
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Ang, R. P. (2007). Factor structure of the 12-item aggression questionnaire: Further evidence from Asian adolescent samples. J Adolesc, 30(4), 671-685. Barnes, K. A., Kaplan, L. A., & Vaidya, C. J. (2007). Developmental differences in cognitive control of socio-affective processing. Dev Neuropsychol, 32(3), 787-807. Bauer, L. O., & Hesselbrock, V. M. (2001). CSD/BEM localization of P300 sources in adolescents "at-risk": evidence of frontal cortex dysfunction in conduct disorder. Biol Psychiatry, 50(8), 600-608. Beaver, K. M. (2011). Genetic influences on being processed through the criminal justice system: results from a sample of adoptees. Biol Psychiatry, 69(3), 282-287. Berman, M. E., & Coccaro, E. F. (1998). Neurobiologic correlates of violence: relevance to criminal responsibility. Behav Sci Law, 16(3), 303-318. Bernstein, I. H., & Gesn, P. R. (1997). On the dimensionality of the Buss/Perry Aggression Questionnaire. Behav Res Ther, 35(6), 563-568. Blair, K. S., Newman, C., Mitchell, D. G., Richell, R. A., Leonard, A., Morton, J., et al. (2006). Differentiating among prefrontal substrates in psychopathy: neuropsychological test findings. Neuropsychology, 20(2), 153-165. Boutwell, B. B., & Beaver, K. M. (2008). A biosocial explanation of delinquency abstention. Crim Behav Ment Health, 18(1), 59-74.
International Journal of Psychological Research - 2011
https://creativecommons.org/licenses/by-nc-sa/4.0/
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https://revistas.usb.edu.co/index.php/IJPR/article/view/804
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Universidad San Buenaventura - USB (Colombia)
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At present there exist a lot of neurobiological and molecular studies that suggest genetic susceptibility to different characteristics of the expression of psychopathy; nevertheless, so far much of those results have not successfully and consistently been replicated, mainly because of the difficulties in: sensitivity, specificity and validity of the clinical evaluation methods; the size and type of the chosen population; and the experimental designs used. Unfortunately, the diagnoses in psychiatry and psychology uses a classification based on prevalence and intensity of the symptoms and do not taken into account the etiology, neurobiology, epidemiology, genetics and response to medication.  The use of limited diagnostic tools analysis and dichotomized the clinical diagnoses lead to a loss of power in the validation of the phenotype being studied and the lack of neurobiological knowledge of the molecules implicated in this kind of disorders, increasing the genetic heterogeneity. This condition obstructs the mapping of susceptibility genes which might outline the neurobiology and pathophysiology of the disease as a central scheme in the conceptualization of the syndrome. This article, we present the most appropriate strategies for examining the phenotype of psychopathy through the use of endophenotypes.
Cuartas Arias, Jorge Mauricio
Psychopathy
cognitive endophenotypes
antisocial personality
Journal article
psychobiology
4
101
https://revistas.usb.edu.co/index.php/IJPR/article/download/804/581
2011-2084
92
2011-06-30T00:00:00Z
2011-06-30T00:00:00Z
https://doi.org/10.21500/20112084.804
10.21500/20112084.804
2011-06-30
2011-7922
institution UNIVERSIDAD DE SAN BUENAVENTURA
thumbnail https://nuevo.metarevistas.org/UNIVERSIDADDESANBUENAVENTURA_COLOMBIA/logo.png
country_str Colombia
collection International Journal of Psychological Research
title Psychobiology and candidate endophenotypes in psychopathy
spellingShingle Psychobiology and candidate endophenotypes in psychopathy
Cuartas Arias, Jorge Mauricio
Psychopathy
cognitive endophenotypes
antisocial personality
psychobiology
title_short Psychobiology and candidate endophenotypes in psychopathy
title_full Psychobiology and candidate endophenotypes in psychopathy
title_fullStr Psychobiology and candidate endophenotypes in psychopathy
title_full_unstemmed Psychobiology and candidate endophenotypes in psychopathy
title_sort psychobiology and candidate endophenotypes in psychopathy
description_eng At present there exist a lot of neurobiological and molecular studies that suggest genetic susceptibility to different characteristics of the expression of psychopathy; nevertheless, so far much of those results have not successfully and consistently been replicated, mainly because of the difficulties in: sensitivity, specificity and validity of the clinical evaluation methods; the size and type of the chosen population; and the experimental designs used. Unfortunately, the diagnoses in psychiatry and psychology uses a classification based on prevalence and intensity of the symptoms and do not taken into account the etiology, neurobiology, epidemiology, genetics and response to medication.  The use of limited diagnostic tools analysis and dichotomized the clinical diagnoses lead to a loss of power in the validation of the phenotype being studied and the lack of neurobiological knowledge of the molecules implicated in this kind of disorders, increasing the genetic heterogeneity. This condition obstructs the mapping of susceptibility genes which might outline the neurobiology and pathophysiology of the disease as a central scheme in the conceptualization of the syndrome. This article, we present the most appropriate strategies for examining the phenotype of psychopathy through the use of endophenotypes.
author Cuartas Arias, Jorge Mauricio
author_facet Cuartas Arias, Jorge Mauricio
topic Psychopathy
cognitive endophenotypes
antisocial personality
psychobiology
topic_facet Psychopathy
cognitive endophenotypes
antisocial personality
psychobiology
citationvolume 4
citationissue 1
publisher Universidad San Buenaventura - USB (Colombia)
ispartofjournal International Journal of Psychological Research
source https://revistas.usb.edu.co/index.php/IJPR/article/view/804
language Inglés
format Article
rights http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
International Journal of Psychological Research - 2011
https://creativecommons.org/licenses/by-nc-sa/4.0/
references_eng Ang, R. P. (2007). Factor structure of the 12-item aggression questionnaire: Further evidence from Asian adolescent samples. J Adolesc, 30(4), 671-685. Barnes, K. A., Kaplan, L. A., & Vaidya, C. J. (2007). Developmental differences in cognitive control of socio-affective processing. Dev Neuropsychol, 32(3), 787-807. Bauer, L. O., & Hesselbrock, V. M. (2001). CSD/BEM localization of P300 sources in adolescents "at-risk": evidence of frontal cortex dysfunction in conduct disorder. Biol Psychiatry, 50(8), 600-608. Beaver, K. M. (2011). Genetic influences on being processed through the criminal justice system: results from a sample of adoptees. Biol Psychiatry, 69(3), 282-287. Berman, M. E., & Coccaro, E. F. (1998). Neurobiologic correlates of violence: relevance to criminal responsibility. Behav Sci Law, 16(3), 303-318. Bernstein, I. H., & Gesn, P. R. (1997). On the dimensionality of the Buss/Perry Aggression Questionnaire. Behav Res Ther, 35(6), 563-568. Blair, K. S., Newman, C., Mitchell, D. G., Richell, R. A., Leonard, A., Morton, J., et al. (2006). Differentiating among prefrontal substrates in psychopathy: neuropsychological test findings. Neuropsychology, 20(2), 153-165. Boutwell, B. B., & Beaver, K. M. (2008). A biosocial explanation of delinquency abstention. Crim Behav Ment Health, 18(1), 59-74.
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url https://revistas.usb.edu.co/index.php/IJPR/article/view/804
url_doi https://doi.org/10.21500/20112084.804
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