Titulo:
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda
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Guardado en:
1794-2470
2462-9448
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2022-12-19
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NOVA - 2023
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Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda Cruz Baquero, Claudia Andrea Bernal Estévez, David Andrés Hernández, Estefania Cuta Flow cytometry minimal residual disease phenotypic differentiation monoclonal antibodies hematological abnormalities acute lymphoblastic leukemia Citometría de flujo enfermedad mínima residual diferenciación fenotípica anticuerpos monoclonales anomalías hematológicas leucemia linfoblástica aguda 20 39 Núm. 39 , Año 2022 : Julio - Diciembre Artículo de revista Journal article 2022-12-19 00:00:00 2022-12-19 00:00:00 2022-12-19 application/pdf Universidad Colegio Mayor de Cundinamarca y Universidad Nacional Abierta y a Distancia - UNAD NOVA 1794-2470 2462-9448 https://revistas.unicolmayor.edu.co/index.php/nova/article/view/2034 10.22490/24629448.6593 https://doi.org/10.22490/24629448.6593 https://creativecommons.org/licenses/by-nc-sa/4.0/ NOVA - 2023 163 180 Instituto Nacional de Salud. Comportamiento epidemiológico de cáncer en menores de 18 años, periodo 2015 a 2020, Colombia. Boletín Epidemiológico Semanal [Internet]. 2021 [citado 5 oct 2020]. Disponible en: https://www.ins.gov.co/buscador-eventos/BoletinEpidemiologico/2021_Boletin_epidemiologico_semana_5.pdf https://doi.org/10.33610/23576189.2021.18 Villalba CP, Martínez PA, Acero H. Caracterización clínico-epidemiológica de los pacientes pediátricos con leucemias agudas en la Clínica Universitaria Colombia. Serie de casos 2011-2014. Pediatría (Santiago) [Internet]. 2016 [citado 14 oct 2020];49(1):17-22. Disponible en: https://www.sciencedirect.com/science/article/pii/S0120491216000148 https://doi.org/10.1016/j.rcpe.2016.01.002 Gacha Garay MJ, Akle V, Enciso L, Garavito Aguilar ZV. La leucemia linfoblástica aguda y modelos animales alternativos para su estudio en Colombia. Rev Colomb Cancerol [Internet]. 2017 [citado 20 oct 2020];21(4):212-224. Disponible en: https://www.revistacancercol.org/index.php/cancer/article/view/182 https://doi.org/10.1016/j.rccan.2016.10.001 Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood [Internet]. 2016 [citado 26 oct 2020];127(20):2391-405. Disponible en: https://ashpublications.org/blood/article/127/20/2391/35255/The-2016-revision-to-the-World-Health-Organization https://doi.org/10.1182/blood-2016-03-643544 Grimwade LF, Fuller KA, Erber WN. Applications of imaging flow cytometry in the diagnostic assessment of acute leukaemia. Methods [Internet]. 2017 [citado 10 nov 2020]; 112:39-45. Disponible en: http://dx.doi.org/10.1016/j.ymeth.2016.06.023 https://doi.org/10.1016/j.ymeth.2016.06.023 Berry DA, Zhou S, Higley H, Mukundan L, Fu S, Reaman GH, et al. Association of minimal residual disease with clinical outcome in pediatric and adult acute lymphoblastic leukemia: A meta-analysis. JAMA Oncol [Internet]. 2017 [citado 17 nov 2020];3(7):1-9. Disponible en: https://jamanetwork.com/journals/jamaoncology/fullarticle/2626509 https://doi.org/10.1001/jamaoncol.2017.0580 Moorman AV. New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia. Haematologica [Internet]. 2016 [citado 25 nov 2020];101(4):407-16. Disponible en: http://www.haematologica.org/lookup/doi/10.3324/haematol.2015.141101 https://doi.org/10.3324/haematol.2015.141101 Sabath DE. Minimal Residual Disease. Leukemia & Lymphoma Society [Internet]. 2018 [citado 25 nov 2020];1(35). Disponible en: https://www.lls.org/sites/default/files/National/USA/Pdf/Publications/FS35_MRD_Final_2019.pdf Terwilliger T, Abdul-Hay M. Acute lymphoblastic leukemia: a comprehensive review and 2017 update. Blood Cancer J [Internet]. 2017 [citado 30 nov 2020];7(6):e577. Disponible en: https://www.nature.com/articles/bcj201753 https://doi.org/10.1038/bcj.2017.53 Tan SH, Bertulfo FC, Sanda T. Leukemia-initiating cells in T-cell acute lymphoblastic leukemia. Front Oncol [Internet]. 2017 [citado 9 dic 2020];7. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2017.00218/full https://doi.org/10.3389/fonc.2017.00218 Fattizzo B, Rosa J, Giannotta JA, Baldini L, Fracchiolla NS. The Physiopathology of T- Cell Acute Lymphoblastic Leukemia: Focus on Molecular Aspects. Front Oncol [Internet]. 2020 [citado 13 dic 2020];10:1-11. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2020.00273/full https://doi.org/10.3389/fonc.2020.00273 Genescà E, Morgades M, Montesinos P, Barba P, Gil C, Guàrdia R, et al. Unique clinico-biological, genetic and prognostic features of adult early T-cell precursor acute lymphoblastic leukemia. Haematologica [Internet]. 2020 [citado 13 dic 2020];105(6):e294-7. Disponible en: https://haematologica.org/article/view/9459 https://doi.org/10.3324/haematol.2019.225078 Heikamp EB, Pui C-H. Next-Generation Evaluation and Treatment of Pediatric Acute Lymphoblastic Leukemia. J Pediatr [Internet]. 2018 [citado 19 dic 2020];203:14-24.e2. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0022347618309442 https://doi.org/10.1016/j.jpeds.2018.07.039 Sentís I, Gonzalez S, Genescà E, García-Hernández V, Muiños F, Gonzalez C, et al. The evolution of relapse of adult T cell acute lymphoblastic leukemia. Genome Biol [Internet]. 2020 [citado 22 dic 2020];21(1):1-24. Disponible en: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02192-z https://doi.org/10.1186/s13059-020-02192-z Iacobucci I, Mullighan CG. Genetic basis of acute lymphoblastic leukemia. J Clin Oncol [Internet]. 2017 [citado 27 dic 2020];35(9):975-83. Disponible en: https://ascopubs.org/doi/10.1200/JCO.2016.70.7836 https://doi.org/10.1200/JCO.2016.70.7836 Van Dongen JJM, Van Der Velden VHJ, Brüggemann M, Orfao A. Minimal residual disease diagnostics in acute lymphoblastic leukemia: Need for sensitive, fast, and standardized technologies. Blood [Internet]. 2015 [citado 5 ene 2021]; 125(26):3996-4009. Disponible en: https://ashpublications.org/blood/article/125/26/3996/34323/Minimal-residual-disease-diagnostics-in-acute https://doi.org/10.1182/blood-2015-03-580027 Wu J, Jia S, Wang C, Zhang W, Liu S, Zeng X, et al. Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing. Front Immunol [Internet]. 2016 [citado 5 ene 2021];7:1-11. Disponible en: http://journal.frontiersin.org/article/10.3389/fimmu.2016.00403 https://doi.org/10.3389/fimmu.2016.00403 Del Príncipe MI, De Bellis E, Gurnari C, Buzzati E, Savi A, Consalvo MAI, et al. Applications and efficiency of flow cytometry for leukemia diagnostics. Expert Rev Mol Diagn [Internet]. 2019 [citado 12 ene 2021];19(12):1089-97. Disponible en: https://doi.org/10.1080/14737159.2019.1691918 https://doi.org/10.1080/14737159.2019.1691918 Azad A, Rajwa B, Pothen A. Immunophenotype discovery, hierarchical organization, and template-based classification of flow cytometry samples. Front Oncol [Internet]. 2016 [citado 17 ene 2021];6(AUG):1-20. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2016.00188/full https://doi.org/10.3389/fonc.2016.00188 Adan A, Alizada G, Kiraz Y, Baran Y, Nalbant A. Flow cytometry: basic principles and applications. Crit Rev Biotechnol [Internet]. 2017 [citado 26 ene 2021];37(2):163-76. Disponible en: https://www.tandfonline.com/doi/full/10.3109/07388551.2015.1128876 https://doi.org/10.3109/07388551.2015.1128876 Tembhare P, Badrinath Y, Ghogale S, Patkar N, Dhole N, Dalavi P, et al. A novel and easy FxCycleTM violet based flow cytometric method for simultaneous assessment of DNA ploidy and six-color immunophenotyping. Cytom Part A [Internet]. 2016 [citado 26 ene 2021];89(3):281-91. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.a.22803 https://doi.org/10.1002/cyto.a.22803 Kalina T, Lundsten K, Engel P. Relevance of Antibody Validation for Flow Cytometry. Cytom Part A [Internet]. 2020 [citado 8 feb 2021];97(2):126-36. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.a.23895 https://doi.org/10.1002/cyto.a.23895 Belver L, Ferrando A. The genetics and mechanisms of T cell acute lymphoblastic leukaemia. Nat Rev Cancer [Internet]. 2016 [citado 12 feb 2021];16(8):494-507. Disponible en: http://dx.doi.org/10.1038/nrc.2016.63 https://doi.org/10.1038/nrc.2016.63 DiGiuseppe JA, Wood BL. Applications of Flow Cytometric Immunophenotyping in the Diagnosis and Posttreatment Monitoring of B and T Lymphoblastic Leukemia/Lymphoma. Cytom Part B - Clin Cytom [Internet]. 2019 [citado 19 feb 2021];96(4):256-65. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/cyto.b.21833 https://doi.org/10.1002/cyto.b.21833 Dong M, Zhang X, Yang Z, Wu S, Ma M, Li Z, et al. Patients over 40 years old with precursor T-cell lymphoblastic lymphoma have different prognostic factors comparing to the youngers. Sci Rep [Internet]. 2018 [citado 25 feb 2021];8(1):1-7. Disponible en: https://www.nature.com/articles/s41598-018-19565-x https://doi.org/10.1038/s41598-018-19565-x Sun J, Wang L, Liu Q, Tárnok A, Su X. Deep learning-based light scattering microfluidic cytometry for label-free acute lymphocytic leukemia classification. Biomed Opt Express [Internet]. 2020 [citado 5 mar 2021];11(11):6674. Disponible en: https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-11-11-6674&id=441886 https://doi.org/10.1364/BOE.405557 Loghavi S, Kutok JL, Jorgensen JL. B-acute lymphoblastic leukemia/lymphoblastic lymphoma. Am J Clin Pathol [Internet]. 2015 [citado 14 mar 2021];144(3):393-410. Disponible en: https://academic.oup.com/ajcp/article/144/3/393/1760791 https://doi.org/10.1309/AJCPAN7BH5DNYWZB Noronha EP, Codeço Marques LV, Andrade FG, Santos Thuler LC, Terra-Granado E, Pombo-De-Oliveira MS. The profile of immunophenotype and genotype aberrations in subsets of pediatric T-cell acute lymphoblastic leukemia. Front Oncol [Internet]. 2019 [citado 22 mar 2021];9:1-10. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2019.00316/full https://doi.org/10.3389/fonc.2019.00316 Rocha JMC, Xavier SG, Souza ME de L, Murao M, de Oliveira BM. Comparison between flow cytometry and standard PCR in the evaluation of MRD in children with acute lymphoblastic leukemia treated with the GBTLI LLA-2009 protocol. Pediatr Hematol Oncol [Internet]. 2019 [citado 30 mar 2021];36(5):287-301. Disponible en: https://doi.org/10.1080/08880018.2019.1636168 https://doi.org/10.1080/08880018.2019.1636168 Rytting ME, Jabbour EJ, O'Brien SM, Kantarjian HM. Acute lymphoblastic leukemia in adolescents and young adults. Cancer [Internet]. 2017 [citado 4 abr 2021];123(13):2398-403. Disponible en: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.30624 https://doi.org/10.1002/cncr.30624 Ministerio de salud y Protección Social. Guía de práctica clínica para la detección, tratamiento y seguimiento de leucemias linfoblásticas y mieloide en población mayor de 18 años. Circulación [Internet]. 2017 [citado 4 abr 2021]; 126: 37. Disponible en: http://gpc.minsalud.gov.co/gpc_sites/Repositorio/Conv_563/GPC_Leucemia_Mayores_18años/LEUCEMIAS - profesionalesDIC29_WEB.pdf Wu J, Jia S, Wang C, Zhang W, Liu S, Zeng X, et al. Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing. Front Immunol [Internet]. 2016 [citado 10 abr 2021]; 7:1-11. Disponible en: http://journal.frontiersin.org/article/10.3389/fimmu.2016.00403 https://doi.org/10.3389/fimmu.2016.00403 Keegan A, Charest K, Schmidt R, Briggs D, Deangelo DJ, Li B, et al. Flow cytometric minimal residual disease assessment of peripheral blood in acute lymphoblastic leukaemia patients has potential for early detection of relapsed extramedullary disease. J Clin Pathol [Internet]. 2018 [citado 18 abr 2021];1-6. Disponible en: https://jcp.bmj.com/content/71/7/653 https://doi.org/10.1136/jclinpath-2017-204828 Fossat C, Roussel M, Arnoux I, Asnafi V, Brouzes C, Garnache-Ottou F, et al. Methodological aspects of minimal residual disease assessment by flow cytometry in acute lymphoblastic leukemia: A french multicenter study. Cytom Part B - Clin Cytom [Internet]. 2015 [citado 24 abr 2021];88(1):21-9. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/cyto.b.21195 https://doi.org/10.1002/cyto.b.21195 Thulasi Raman R, Anurekha M, Lakshman V, Balasubramaniam R, Ramya U, Revathi R. Immunophenotypic modulation in pediatric B lymphoblastic leukemia and its implications in MRD detection. Leuk Lymphoma [Internet]. 2020 [citado 24 abr 2021];61(8):1974-80. Disponible en: https://doi.org/10.1080/10428194.2020.1742902 https://doi.org/10.1080/10428194.2020.1742902 Ravandi F, Jorgensen JL, O'Brien SM, Jabbour E, Thomas DA, Borthakur G, et al. Minimal residual disease assessed by multi-parameter flow cytometry is highly prognostic in adult patients with acute lymphoblastic leukaemia. Br J Haematol [Internet]. 2016 [citado 30 abr 2021];172(3):392-400. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.13834 https://doi.org/10.1111/bjh.13834 Li HF, Meng WT, Jia YQ, Jiang NG, Zeng TT, Jin YM, et al. Development-Associated immunophenotypes reveal the heterogeneous and individualized early responses of adult B-Acute lymphoblastic leukemia. Med (United States) [Internet]. 2016 [citado 6 may 2021];95(34). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400307/ https://doi.org/10.1097/MD.0000000000004128 Li SQ, Fan QZ, Xu LP, Wang Y, Zhang XH, Chen H, et al. Different Effects of Pre-transplantation Measurable Residual Disease on Outcomes According to Transplant Modality in Patients With Philadelphia Chromosome Positive ALL. Front Oncol [Internet]. 2020 [citado 15 may 2021];10(March):1-13. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2020.00320/ful https://doi.org/10.3389/fonc.2020.00320 Keeney M, Hedley BD, Chin-Yee IH. Flow cytometry-Recognizing unusual populations in leukemia and lymphoma diagnosis. Int J Lab Hematol [Internet]. 2017 [citado 21 may 2021];39:86-92. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1111/ijlh.12666 https://doi.org/10.1111/ijlh.12666 Marsán Suárez V, Macías Abraham C, Díaz Domínguez G, Morales Garrido Y, Lam Díaz RM, Machín García S, González Otero A, et al. Expresión del antígeno CD45 en la Leucemia Linfoide aguda Pediátrica. Rev Cubana Hematol Inmunol Hemoter [Internet]. 2017 [citado 21 may 2021]; 33(2):[aprox. 0 p.]. Disponible en: http://www.revhematologia.sld.cu/index.php/hih/article/view/513 Wood BL. Principles of minimal residual disease detection for hematopoietic neoplasms by flow cytometry. Cytom Part B - Clin Cytom [Internet]. 2016 [citado 8 jun 2021];90(1):47-53. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1002/cyto.b.21239 https://doi.org/10.1002/cyto.b.21239 Chatterjee T, Mallhi RS, Venkatesan S. Minimal residual disease detection using flow cytometry: Applications in acute Leukemia. Med J Armed Forces India [Internet]. 2016 [citado 8 jun 2021];72(2):152-6. Available from: http://dx.doi.org/10.1016/j.mjafi.2016.02.002 https://doi.org/10.1016/j.mjafi.2016.02.002 Chen X, Wood BL. Monitoring minimal residual disease in acute leukemia: Technical challenges and interpretive complexities. Blood Rev [Internet]. 2017 [citado 23 jun 2021];31(2):63-75. Disponible en: http://dx.doi.org/10.1016/j.blre.2016.09.006 https://doi.org/10.1016/j.blre.2016.09.006 Wenzinger C, Williams E, Gru AA. Updates in the Pathology of Precursor Lymphoid Neoplasms in the Revised Fourth Edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. Curr Hematol Malig Rep [Internet]. 2018 [citado 30 jun 2021];13(4):275-88. Disponible en: https://link.springer.com/article/10.1007/s11899-018-0456-8 https://doi.org/10.1007/s11899-018-0456-8 Xia M, Zhang H, Lu Z, Gao Y, Liao X, Li H. Key markers of minimal residual disease in childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol [Internet]. 2016 [citado 6 jul 2021];38(6):418-22. Disponible en: https://journals.lww.com/jpho-online/Abstract/2016/08000/Key_Markers_of_Minimal_Residual_Disease_in.2.aspx https://doi.org/10.1097/MPH.0000000000000624 Popov A, Henze G, Verzhbitskaya T, Roumiantseva J, Lagoyko S, Khlebnikova O, et al. Absolute count of leukemic blasts in cerebrospinal fluid as detected by flow cytometry is a relevant prognostic factor in children with acute lymphoblastic leukemia. J Cancer Res Clin Oncol [Internet]. 2019 [citado 6 jul 2021];145(5):1331-9. Disponible en: http://dx.doi.org/10.1007/s00432-019-02886-3 https://doi.org/10.1007/s00432-019-02886-3 McShane LM, Smith MA. Prospects for Minimal Residual Disease as a Surrogate Endpoint in Pediatric Acute Lymphoblastic Leukemia Clinical Trials. JNCI Cancer Spectrum [Internet]. 2018 [citado 17 jul 2021]; 2(4):pky070. Disponible en: https://doi.org/10.1093/jncics/pky070 https://doi.org/10.1093/jncics/pky070 Karawajew L, Dworzak M, Ratei R, Rhein P, Gaipa G, Buldini B, et al. Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia. Haematologica [Internet]. 2015 [citado 26 jul 2021];100(7):935-44. Disponible en: https://haematologica.org/article/view/7439 https://doi.org/10.3324/haematol.2014.116707 Bruggemann M, Kotrova M. Minimal residual disease in adult ALL: Technical aspects and implications for correct clinical interpretation. Blood Adv [Internet]. 2017 [citado 31 jul 2021];1(25):2456-66. Disponible en: https://ashpublications.org/hematology/article/2017/1/13/21072/Minimal-residual-disease-in-adult-ALL-technical https://doi.org/10.1182/bloodadvances.2017009845 Walter RB, Gooley TA, Wood BL, Milano F, Fang M, Sorror ML, et al. Impact of pretransplantation minimal residual disease, as detected by multiparametric flow cytometry, on outcome of myeloablative hematopoietic cell transplantation for acute myeloid leukemia. J Clin Oncol [Internet]. 2011 [citado 22 ago 2021];29(9):1190-7. Disponible en: https://www.hindawi.com/journals/lrt/2014/421723/ https://doi.org/10.1200/JCO.2010.31.8121 Gökbuget N. How should we treat a patient with relapsed Ph-negative B-ALL and what novel approaches are being investigated? Best Pract Res Clin Haematol [Internet]. 2017 [citado 22 ago 2021];30(3):261-74. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S1521692617300270?via%3Dihub https://doi.org/10.1016/j.beha.2017.07.010 Tembhare PR, Narula G, Khanka T, Ghogale S, Chatterjee G, Patkar N V., et al. Post-induction Measurable Residual Disease Using Multicolor Flow Cytometry Is Strongly Predictive of Inferior Clinical Outcome in the Real-Life Management of Childhood T-Cell Acute Lymphoblastic Leukemia: A Study of 256 Patients. Front Oncol [Internet]. 2020 [citado 22 ago 2021];10(April):1-13. Disponible en: https://www.frontiersin.org/articles/10.3389/fonc.2020.00577/full https://doi.org/10.3389/fonc.2020.00577 Schrappe M. Detection and management of minimal residual disease in acute lymphoblastic leukemia. Hematol (United States) [Internet]. 2014 [citado 29 ago 2021];2014(1):244-9. Available from: https://ashpublications.org/hematology/article/2014/1/244/20518/Detection-and-management-of-minimal-residual https://doi.org/10.1182/asheducation-2014.1.244 Kruse A, Abdel-Azim N, Kim HN, Ruan Y, Phan V, Ogana H, et al. Minimal residual disease detection in acute lymphoblastic leukemia. Int J Mol Sci [Internet]. 2020 [citado 29 ago 2021];21(3). Disponible en: https://www.mdpi.com/1422-0067/21/3/1054/htm https://doi.org/10.3390/ijms21031054 Abou Dalle I, Jabbour E, Short NJ. Evaluation and management of measurable residual disease in acute lymphoblastic leukemia. Ther Adv Hematol [Internet]. 2020 [citado 06 sep 2021];11:204062072091002. Disponible en: https://journals.sagepub.com/doi/10.1177/2040620720910023 https://doi.org/10.1177/2040620720910023 Hoelzer D, Bassan R, Dombret H, Fielding A, Ribera JM, Buske C, et al. Acute lymphoblastic leukaemia in adult patients: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol [Internet]. 2016 [citado 06 sep 2021];27:v69-82. Disponible en: http://dx.doi.org/10.1093/annonc/mdw025 https://doi.org/10.1093/annonc/mdw025 Pui C-H, Pei D, Raimondi SC, Coustan-Smith E, Jeha S, Cheng C, et al. Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with Response-Adapted therapy. Leukemia [Internet]. 2017 [citado 06 sep 2021];31(2):333-9. Available from: http://www.nature.com/articles/leu2016234 https://doi.org/10.1038/leu.2016.234 Campana D, Pui C. Evidence-Based Focused Review Minimal residual disease - guided therapy in childhood acute lymphoblastic leukemia Case presentations. Blood [Internet]. 2017 [citado 06 sep 2021];129(14):1913-9. Disponible en: https://ashpublications.org/blood/article/129/14/1913/35887/Minimal-residual-disease-guided-therapy-in https://doi.org/10.1182/blood-2016-12-725804 Jabbour E, O'Brien S, Konopleva M, Kantarjian H. New insights into the pathophysiology and therapy of adult acute lymphoblastic leukemia. Cancer [Internet]. 2015 [citado 06 sep 2021];121(15):2517-28. Disponible en: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.29383 https://doi.org/10.1002/cncr.29383 Raetz EA, Teachey DT. T-cell acute lymphoblastic leukemia. Hematology [Internet]. 2016 [citado 06 sep 2021];2016(1):580-8. Disponible en: https://ashpublications.org/hematology/article/2016/1/580/21136/T-cell-acute-lymphoblastic-leukemia https://doi.org/10.1182/asheducation-2016.1.580 https://revistas.unicolmayor.edu.co/index.php/nova/article/download/2034/3053 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/redcol/resource_type/ARTREF info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
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UNIVERSIDAD COLEGIO MAYOR DE CUNDINAMARCA |
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Colombia |
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NOVA |
| title |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| spellingShingle |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda Cruz Baquero, Claudia Andrea Bernal Estévez, David Andrés Hernández, Estefania Cuta Flow cytometry minimal residual disease phenotypic differentiation monoclonal antibodies hematological abnormalities acute lymphoblastic leukemia Citometría de flujo enfermedad mínima residual diferenciación fenotípica anticuerpos monoclonales anomalías hematológicas leucemia linfoblástica aguda |
| title_short |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| title_full |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| title_fullStr |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| title_full_unstemmed |
Enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| title_sort |
enfermedad mínima residual por citometría de flujo en pacientes con leucemia linfoblástica aguda |
| author |
Cruz Baquero, Claudia Andrea Bernal Estévez, David Andrés Hernández, Estefania Cuta |
| author_facet |
Cruz Baquero, Claudia Andrea Bernal Estévez, David Andrés Hernández, Estefania Cuta |
| topic |
Flow cytometry minimal residual disease phenotypic differentiation monoclonal antibodies hematological abnormalities acute lymphoblastic leukemia Citometría de flujo enfermedad mínima residual diferenciación fenotípica anticuerpos monoclonales anomalías hematológicas leucemia linfoblástica aguda |
| topic_facet |
Flow cytometry minimal residual disease phenotypic differentiation monoclonal antibodies hematological abnormalities acute lymphoblastic leukemia Citometría de flujo enfermedad mínima residual diferenciación fenotípica anticuerpos monoclonales anomalías hematológicas leucemia linfoblástica aguda |
| citationvolume |
20 |
| citationissue |
39 |
| citationedition |
Núm. 39 , Año 2022 : Julio - Diciembre |
| publisher |
Universidad Colegio Mayor de Cundinamarca y Universidad Nacional Abierta y a Distancia - UNAD |
| ispartofjournal |
NOVA |
| source |
https://revistas.unicolmayor.edu.co/index.php/nova/article/view/2034 |
| language |
|
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ NOVA - 2023 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
| type_driver |
info:eu-repo/semantics/article |
| type_coar |
http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
| type_coarversion |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2022-12-19 |
| date_accessioned |
2022-12-19 00:00:00 |
| date_available |
2022-12-19 00:00:00 |
| url |
https://revistas.unicolmayor.edu.co/index.php/nova/article/view/2034 |
| url_doi |
https://doi.org/10.22490/24629448.6593 |
| issn |
1794-2470 |
| eissn |
2462-9448 |
| doi |
10.22490/24629448.6593 |
| citationstartpage |
163 |
| citationendpage |
180 |
| url2_str_mv |
https://revistas.unicolmayor.edu.co/index.php/nova/article/download/2034/3053 |
| _version_ |
1811200276838744064 |