Titulo:
Estados hipertensivos en el embarazo: revisión
.
Sumario:
La enfermedad hipertensiva en el embarazo es una de las primeras causas de morbimortalidad. La siguiente revisión pretende dar una visión de su fisiopatología, a la luz de la biología molecular. Se analizan los factores de riesgo, basados en la evidencia, el diagnóstico y el manejo, según las guías nacionales e internacionales, que permite tener un enfoque actualizado de una patología frecuente, para el especialista y para el médico general. Los autores desean que este documento sea de utilidad en la práctica médica.  
Guardado en:
0123-4226
2619-2551
17
2015-12-31
311
323
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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metarevistapublica_udca_revistau.d.c.aactualidad_divulgacioncientifica_94_article_233 |
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ojs |
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Estados hipertensivos en el embarazo: revisión Pregnancy hypertensive states: review La enfermedad hipertensiva en el embarazo es una de las primeras causas de morbimortalidad. La siguiente revisión pretende dar una visión de su fisiopatología, a la luz de la biología molecular. Se analizan los factores de riesgo, basados en la evidencia, el diagnóstico y el manejo, según las guías nacionales e internacionales, que permite tener un enfoque actualizado de una patología frecuente, para el especialista y para el médico general. Los autores desean que este documento sea de utilidad en la práctica médica.   Hypertensive disease in pregnancy is one of the leading causes of morbidity and mortality. The following review aims to give an overview of its pathophysiology in the light of molecular biology, to analyze the risk factors based on the evidence, diagnosis and management according to national and international guidelines allows us to have an updated view of a common pathology for specialist and the general practitioner. The authors wish that this document will be useful in medical practice. Beltrán Chaparro, Lina Vanessa Benavides, Pablo López Rios, Jesús A. Onatra Herrera, William Hipertensión y embarazo pre eclampsia eclampsia síndrome HELLP Hypertension and pregnancy preeclampsia eclampsia HELLP syndrome 17 2 Núm. 2 , Año 2014 :Revista U.D.C.A Actualidad & Divulgación Científica. Julio-Diciembre Artículo de revista Journal article 2014-12-31T00:00:00Z 2014-12-31T00:00:00Z 2015-12-31 application/pdf text/html Universidad de Ciencias Aplicadas y Ambientales U.D.C.A Revista U.D.C.A Actualidad & Divulgación Científica 0123-4226 2619-2551 https://revistas.udca.edu.co/index.php/ruadc/article/view/233 10.31910/rudca.v17.n2.2014.233 https://doi.org/10.31910/rudca.v17.n2.2014.233 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ 311 323 ABALOS, E.; DULEY, L.; STEYN, D.W. 2014. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. Cochrane Database Syst. Rev. 6;2:CD002252. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS (ACOG). 2012. Practice Bulletin No. 125: Chronic hypertension in pregnancy. Obstet. Gynecol. 119(2):396-407. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS (ACOG). 2013. Task Force on Hypertension in Pregnancy. Obstet Gynecol. 122(5):1122-1131. ASKIE, L.M.; DULEY, L.; HENDERSON-SMART, D.J.; STEWART, L.A. 2007. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. Lancet. 369 (9575):1791-1798. BATEMAN, B.T.; SHAW, K.M.; KUKLINA, E.V.; CALLAGHAN, W.M.; SEELY, E.W.; HERNÁNDEZ-DÍAZ, S. 2012. Hypertension in women of reproductive age in the United States: NHANES 1999-2008. PLoS One Apr 7(4):e36171. BOUCOIRAN, I.; THISSIER-LEVY, S.; WU, Y.; WEI, S.Q.; LUO, Z.C.; DELVIN, E.; FRASER, W.D.; AUDIBERT, F.; MIROS STUDY GROUP. 2013. Risks for preeclampsia and small for gestational age: predictive values of placental growth factor, soluble fms-like tyrosine kinase-1, and inhibin. A in singleton and multiplegestation pregnancies. Am. J. Perinat. 30(7):607-12. BRENNAN, L.J.; MORTON, J.S.; DAVIDGE, S.T. 2014. Vascular dysfunction in preeclampsia. Microcirculation 21(1):4-14. BRYANT, A.S.; SEELY, E.W.; COHEN, A.; LIEBERMAN, E. 2005. Patterns of pregnancy-related hypertension in black and white women. Hypertens. Pregnancy. 24(3):281-290. BUITRAGO, G.G.; CASTRO, A.S.; CIFUENTES, R.B.; OSPINO, M.P.G., ARÉVALO, I.R.; GÓMEZ, P.L. 2013. Guía de Práctica Clínica para el abordaje de las complicaciones hipertensivas asociadas al embarazo. Rev. Col. Obstet. Ginecol. 64(3):289-326. CHANG, S.H.; KANASAKI, K.; GOCHEVA, V.; BLUM, G.; HARPER, J.; MOSES, M.A.; SHIH, S.C.; NAGY, J.A.; JOYCE, J.; BOGYO, M.; KALLURI, R.; DVORAK, H.F. 2009. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 69(10):4537-4544. CNOSSEN, J.S.; VOLLEBREGT, K.C.; DE VRIEZE, N.; TER RIET, G.; MOL, B.W.; FRANX, A.; KHAN, K.S.; VAN DER POST, J.A. 2008. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ. 336:1117-1120. CONNOR-GORBER, S.; SINGH, H.; POTTIE, K.; JARAMILLO, A.; TONELLI, M. 2012. Process for guideline development by the reconstituted Canadian Task Force on Preventive Health Care. CMAJ. 184(14):1575-81. 13. COX, B.; SHARMA, P.; EVANGELOU, A.I.; WHITELEY, K.; IGNATCHENKO, V.; IGNATCHENKO, A.; BACZYK, D.; CZIKK, M.; KINGDOM, J.; ROSSANT, J.; GRAMOLINI, A.O.; ADAMSON, S.L.; KISLINGER, T. 2011. Translational analysis of mouse and human placental protein and mRNA reveals distinct molecular pathologies in human preeclampsia. Mol Cell Proteomics. 10(12):M111.012526. DE MAAT, M.P.; DE GROOT, C.J. 2011. Thrombophi lia and pre-eclampsia. Semin Thromb Hemost. 37(2):106-110. DULEY, L.; GÜLMEZOGLU, A.M.; HENDERSON-SMART, D.J.; CHOU, D. 2010. Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database Syst. Rev. 10;(11) CD000025. DVORAK, H.F. 2002. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J. Clin. Oncol. 20:4368-4380. ESTRADA-GUTIÉRREZ, G.; CAPPELLO, R.E.; MISHRA, N.; ROMERO, R.; STRAUSS, J.F.; WALSH, S.W. 2011. Increased expression of matrix metalloprotei nase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction. Am. J. Pathol. 178(1):451-460. FESCINA, R.H.; DE MUCIO, B.; MARTÍNEZ, G.; DIAZ ROSSELLO, J.L.; MAINERO, L.; RUBINO, M. 2010. Instrucciones de llenado y definicion de la historia clinica perinatal. CLAP / OMS / SMR. No 1572: 1-82. FILHO, E.V.; MOHR, C.; ACAUAN FILHO, B.J.; GADONSKI, G.; PAULA, L.G.; FERREIRA ANTONELLO, I.C.; POLI-DE-FIGUEIREDO, C.E.; PINHEIRODA-COSTA, B.E. 2010. A Flow-mediated dilatation in the differential diagnosis of preeclampsia syndrome. Arq. Bras. Cardiol. 94(2):195-200. FLACK, J.M.; KEITH, C.; FERDINAND, K.C.; NASSER, S.A.; ROSSI, N.F. 2010. Hypertension in special populations: chronic kidney disease, organ transplant recipients, pregnancy, autonomic dysfunction, racial and ethnic Populations. Cardiol. Clin. 28(4):623-638. GARZÓN, D.; AGUDELO, C.C.; PARDO, R.; GAITÁN, H.; GÓMEZ, P.I.; PINILLA, A.R.; BUSTOS, J.C.; SÁNCHEZ, C.L.; PINEDA, F. 2010. Guia 14. Atencion de las complicaciones hipertensivas asociadas al embarazo. Ministerio de la Proteccion Social. Secretaria de Salud de Bogota. p.37-52. GRILL, S.; RUSTERHOLZ, C.; ZANETTI-DÄLLENBACH, R.; TERCANLI, S.; HOLZGREVE, W.; HAHN, S.; LAPAIRE, O. 2009. Potential markers of preeclampsia: a review. Reprod. Biol. Endocrin. 14:7-70. HAUTH, J.C.; EWELL, M.G.; LEVINE, R.J.; ESTERLITZ, J.R.; SIBAI, B.; CURET, L.B.; CATALANO, P.M.; MORRIS, C.D. 2000. Pregnancy outcomes in healthy nulliparas who developed hypertension. Calcium for Preeclampsia Prevention Study Group. Obstet. Gynecol. 95(1):24-28. HENRIQUES, A.C.; CARVALHO, F.H.; FEITOSA, H.N.; MACENA, R.H.; MOTA, R.M.; ALENCAR, J. 2014. Endothelial dysfunction after pregnancy induced hypertension. Int J Gynaecol Obstet 124(3):230-234. JAMES, P.R.; NELSON-PIERCY, C. 2004. Management of hypertension before, during, and after pregnancy. Heart. 90:1499-1504. LASH, G.E.; NARUSE, K.; ROBSON, A.; INNES, B.A.; SEARLE, R.F.; ROBSON, S.C.; BULMER, J.N. 2011. Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production. Hum. Reprod. 26(9):2289-2295. LATA, I. 2013. Hepatobiliary diseases during pregnancy and their management: An update. Int. J. Crit. Illn. In.j Sci. 3(3):175-182. LEEMAN, L.; FONTAINE, P. 2008. Hypertensive disorders of pregnancy. Am. Fam. Physician. 78:93-100. LEIS MÁRQUEZ, M.T.; RODRÍGUEZ BOSCH, M.R.; GARCÍA LÓPEZ, M.A. 2010. Guías del Colegio Mexicano de Especialistas en Ginecología y Obstetricia. Ginecol. Obstet. Mex. 78(6):S461-525. LINDHEIMER, M.D.; KANTER D. 2010. Interpreting abnormal proteinuria in pregnancy. Obstet. Gynecol. 115:365-375. LYALL, F.; ROBSON, S.C.; BULMER, J.N. 2013. Spiral artery remodeling and trophoblast invasion in preeclampsia and fetal growth restriction: relationship to clinical outcome. Hypertension 62(6):1046-1054. LOWE, S.A.; BROWN, M.A.; DEKKER, G.A.; GATT, S.; MCLINTOCK, C.K.; MCMAHON, L.P.; MANGOS, G.; MOORE, M.P.; MULLER, P.; PAECH, M.; WALTERS, B. 2009. Guidelines for the management of hypertensive disorders of pregnancy 2008. Aus. N. Z. J. Obstet. Gynecol. 49(3):242-246. MAGEE, L.; HELEWEA, M.; MOUTQUIN, J.M.; VON DADLSZEN, P. 2008. .Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy. Hypertension Guideline Committee; Strategic Training Initiative in Research in the Reproductive Health Sciences (STIRRHS) Scholars. J. Obstet. Gynaecol. Can. 30(3 Suppl):S1-48. MELER, E.; FIGUERAS, F.; BENNASAR, M.; GOMEZ, O.; CRISPI, F.; GRATACOS, E. 2010. The prognostic role of uterine artery Doppler investigation in patients with severe early-onset preeclampsia. Am. J. Obstet. Gynecol. 202(6):559.E1-4. MOHAJERTEHRAN, F.; TAVAKKOL AFSHARI, J.; REZAIEYAZDI, Z.; GHOMIAN, N. 2012. Association of single nucleotide polymorphisms in the human tumor necrosis factor-α and interleukin 1-β genes in patients with pre-eclampsia. Iran J. Allergy Asthma Immunol. 11(3):224-229. MORI, T.; WATANABE, K.; IWASAKI, A.; KIMURA, C.; MATSUSHITA, H.; SHINOHARA, K.; WAKATSUKI, A. 2014. Differences in vascular reactivity between pregnant women with chronic hypertension and preeclampsia. Hypertens. Res. 37(2):145-150. MUTZE, S.; RUDNIK-SCHONEBORN, S.; ZERRES, K.; RATH, W. 2008. Genes and the preeclampsia syndrome. J. Perinat. Med. 36(1):38-58. QI, H.P.; FRASER, W.D.; LUO, Z.C.; JULIEN, P.; AUDIBERT, F.; WEI, S.Q. 2013. Endothelial nitric oxide synthase gene polymorphisms and risk of preeclampsia. Am. J. Perinatol. 30(10):795-804. RANA, S.; KARUMANCHI, S.A.; LINDHEIMER, M.D. 2014. Angiogenic factors in diagnosis, management, and research in preeclampsia. Hypertension. 63(2):198-202. ROBERTS, J.M.; MYATT, L.; SPONG, C.Y.; THOM, E.A.; HAUTH, J.C.; LEVENO, K.J.; PEARSON, G.D.; WAPNER, R.J.; VARNER, M.W.; THORP, J.M. JR.; MERCER, B.M.; PEACEMAN, A.M.; RAMIN, S.M.; CARPENTER, M.W.; SAMUELS, P.; SCISCIONE, A.; HARPER, M.; SMITH, W.J.; SAADE, G.; SOROKIN, Y.; ANDERSON, G.B. 2010. Vitamins C and E to prevent complications of pregnancy-associated hypertension. N. Engl. J. Med. 362(14):1282-1291. ROYAL COLLEGE OBSTETRICIANS AND GYNAECOLOGY (RCOG). 2011. Hypertension in pregnancy: The management of hypertensive disorders during pregnancy. NICE Clinical guideline. 107:2-53. SAVAJ, S.; VAZIRI, N.D. 2012. An overview of recent advances in pathogenesis and diagnosis of preeclampsia. IJKD. 6(5):334-338. SHARMA, S.; SINGH, M.; SHARMA, P.L. 2013 Mechanism of hyperhomocysteinemia-induced vascular endothelium dysfunction possible dysregulation of phosphatidylinositol-3-kinase and its downstream phosphoinositide dependent kinase and protein kinase B. Eur. J. Pharmacol. 721(1-3):365-372. SIBAI, B.M. 2003. Diagnosis and management of gestational hypertension and preeclampsia. Obstet. Gynecol. 102:181-192. TATE, J.; BUSHNELL, C. 2011. Pregnancy and stroke risk in women. Womens Health (England). 7(3):363-74. THE SOCIETY OF OBSTETRICIANS AND GYNAECOLOGISTS OF CANADA (SCOG). 2008. Diagnosis, evaluation and management of the hypertensive disorders of pregnancy. J. Obstet. Gynaecol. Can. 30(3):S1-S380. TURNER, J.A. 2010. Diagnosis and management of pre-eclampsia: an update. Interl J. Women's Health. 2:327-337. VEERBEEK, J.H.; SMIT, J.G.; KOSTER, M.P.; POST UITERWEER, E.D.; VAN RIJN, B.B.; KOENEN, S.V.; FRANX, A. 2013 Maternal cardiovascular risk profile after placental abruption. Hypertension. 61(6):1297- 1301. VEST, A.R.; CHO, L.S. 2014. Hypertension in pregnancy. Curr. Atheroscler. Rep. 16(3):395. WILLIAMS, P.J.; MORGAN, L. 2012.The role of genetics in pre-eclampsia and potential pharmacogenomic interventions. Pharmacog. Pers. Med. 5:37-51. ZAFARMAND, M.H.; NIJDAM, M.E.; FRANX, A.; GROBBEE, D.E.; BOTS, M.L. 2008 The angiotensinogen gene M235T polymorphism and development of preeclampsia / eclampsia: a meta-analysis and meta-regression of observational studies. J. Hypertens. 26(9):1726-1734. https://revistas.udca.edu.co/index.php/ruadc/article/download/233/189 https://revistas.udca.edu.co/index.php/ruadc/article/download/233/1203 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/redcol/resource_type/ARTREF info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
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UNIVERSIDAD DE CIENCIAS APLICADAS Y AMBIENTALES |
| thumbnail |
https://nuevo.metarevistas.org/UNIVERSIDADDECIENCIASAPLICADASYAMBIENTALES/logo.png |
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Colombia |
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Revista U.D.C.A Actualidad & Divulgación Científica |
| title |
Estados hipertensivos en el embarazo: revisión |
| spellingShingle |
Estados hipertensivos en el embarazo: revisión Beltrán Chaparro, Lina Vanessa Benavides, Pablo López Rios, Jesús A. Onatra Herrera, William Hipertensión y embarazo pre eclampsia eclampsia síndrome HELLP Hypertension and pregnancy preeclampsia eclampsia HELLP syndrome |
| title_short |
Estados hipertensivos en el embarazo: revisión |
| title_full |
Estados hipertensivos en el embarazo: revisión |
| title_fullStr |
Estados hipertensivos en el embarazo: revisión |
| title_full_unstemmed |
Estados hipertensivos en el embarazo: revisión |
| title_sort |
estados hipertensivos en el embarazo: revisión |
| title_eng |
Pregnancy hypertensive states: review |
| description |
La enfermedad hipertensiva en el embarazo es una de las primeras causas de morbimortalidad. La siguiente revisión pretende dar una visión de su fisiopatología, a la luz de la biología molecular. Se analizan los factores de riesgo, basados en la evidencia, el diagnóstico y el manejo, según las guías nacionales e internacionales, que permite tener un enfoque actualizado de una patología frecuente, para el especialista y para el médico general. Los autores desean que este documento sea de utilidad en la práctica médica.
 
|
| description_eng |
Hypertensive disease in pregnancy is one of the leading causes of morbidity and mortality. The following review aims to give an overview of its pathophysiology in the light of molecular biology, to analyze the risk factors based on the evidence, diagnosis and management according to national and international guidelines allows us to have an updated view of a common pathology for specialist and the general practitioner. The authors wish that this document will be useful in medical practice.
|
| author |
Beltrán Chaparro, Lina Vanessa Benavides, Pablo López Rios, Jesús A. Onatra Herrera, William |
| author_facet |
Beltrán Chaparro, Lina Vanessa Benavides, Pablo López Rios, Jesús A. Onatra Herrera, William |
| topicspa_str_mv |
Hipertensión y embarazo pre eclampsia eclampsia síndrome HELLP |
| topic |
Hipertensión y embarazo pre eclampsia eclampsia síndrome HELLP Hypertension and pregnancy preeclampsia eclampsia HELLP syndrome |
| topic_facet |
Hipertensión y embarazo pre eclampsia eclampsia síndrome HELLP Hypertension and pregnancy preeclampsia eclampsia HELLP syndrome |
| citationvolume |
17 |
| citationissue |
2 |
| citationedition |
Núm. 2 , Año 2014 :Revista U.D.C.A Actualidad & Divulgación Científica. Julio-Diciembre |
| publisher |
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A |
| ispartofjournal |
Revista U.D.C.A Actualidad & Divulgación Científica |
| source |
https://revistas.udca.edu.co/index.php/ruadc/article/view/233 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
| references |
ABALOS, E.; DULEY, L.; STEYN, D.W. 2014. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. Cochrane Database Syst. Rev. 6;2:CD002252. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS (ACOG). 2012. Practice Bulletin No. 125: Chronic hypertension in pregnancy. Obstet. Gynecol. 119(2):396-407. AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS (ACOG). 2013. Task Force on Hypertension in Pregnancy. Obstet Gynecol. 122(5):1122-1131. ASKIE, L.M.; DULEY, L.; HENDERSON-SMART, D.J.; STEWART, L.A. 2007. Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data. Lancet. 369 (9575):1791-1798. BATEMAN, B.T.; SHAW, K.M.; KUKLINA, E.V.; CALLAGHAN, W.M.; SEELY, E.W.; HERNÁNDEZ-DÍAZ, S. 2012. Hypertension in women of reproductive age in the United States: NHANES 1999-2008. PLoS One Apr 7(4):e36171. BOUCOIRAN, I.; THISSIER-LEVY, S.; WU, Y.; WEI, S.Q.; LUO, Z.C.; DELVIN, E.; FRASER, W.D.; AUDIBERT, F.; MIROS STUDY GROUP. 2013. Risks for preeclampsia and small for gestational age: predictive values of placental growth factor, soluble fms-like tyrosine kinase-1, and inhibin. A in singleton and multiplegestation pregnancies. Am. J. Perinat. 30(7):607-12. BRENNAN, L.J.; MORTON, J.S.; DAVIDGE, S.T. 2014. Vascular dysfunction in preeclampsia. Microcirculation 21(1):4-14. BRYANT, A.S.; SEELY, E.W.; COHEN, A.; LIEBERMAN, E. 2005. Patterns of pregnancy-related hypertension in black and white women. Hypertens. Pregnancy. 24(3):281-290. BUITRAGO, G.G.; CASTRO, A.S.; CIFUENTES, R.B.; OSPINO, M.P.G., ARÉVALO, I.R.; GÓMEZ, P.L. 2013. Guía de Práctica Clínica para el abordaje de las complicaciones hipertensivas asociadas al embarazo. Rev. Col. Obstet. Ginecol. 64(3):289-326. CHANG, S.H.; KANASAKI, K.; GOCHEVA, V.; BLUM, G.; HARPER, J.; MOSES, M.A.; SHIH, S.C.; NAGY, J.A.; JOYCE, J.; BOGYO, M.; KALLURI, R.; DVORAK, H.F. 2009. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 69(10):4537-4544. CNOSSEN, J.S.; VOLLEBREGT, K.C.; DE VRIEZE, N.; TER RIET, G.; MOL, B.W.; FRANX, A.; KHAN, K.S.; VAN DER POST, J.A. 2008. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and meta-analysis. BMJ. 336:1117-1120. CONNOR-GORBER, S.; SINGH, H.; POTTIE, K.; JARAMILLO, A.; TONELLI, M. 2012. Process for guideline development by the reconstituted Canadian Task Force on Preventive Health Care. CMAJ. 184(14):1575-81. 13. COX, B.; SHARMA, P.; EVANGELOU, A.I.; WHITELEY, K.; IGNATCHENKO, V.; IGNATCHENKO, A.; BACZYK, D.; CZIKK, M.; KINGDOM, J.; ROSSANT, J.; GRAMOLINI, A.O.; ADAMSON, S.L.; KISLINGER, T. 2011. Translational analysis of mouse and human placental protein and mRNA reveals distinct molecular pathologies in human preeclampsia. Mol Cell Proteomics. 10(12):M111.012526. DE MAAT, M.P.; DE GROOT, C.J. 2011. Thrombophi lia and pre-eclampsia. Semin Thromb Hemost. 37(2):106-110. DULEY, L.; GÜLMEZOGLU, A.M.; HENDERSON-SMART, D.J.; CHOU, D. 2010. Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. Cochrane Database Syst. Rev. 10;(11) CD000025. DVORAK, H.F. 2002. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J. Clin. Oncol. 20:4368-4380. ESTRADA-GUTIÉRREZ, G.; CAPPELLO, R.E.; MISHRA, N.; ROMERO, R.; STRAUSS, J.F.; WALSH, S.W. 2011. Increased expression of matrix metalloprotei nase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction. Am. J. Pathol. 178(1):451-460. FESCINA, R.H.; DE MUCIO, B.; MARTÍNEZ, G.; DIAZ ROSSELLO, J.L.; MAINERO, L.; RUBINO, M. 2010. Instrucciones de llenado y definicion de la historia clinica perinatal. CLAP / OMS / SMR. No 1572: 1-82. FILHO, E.V.; MOHR, C.; ACAUAN FILHO, B.J.; GADONSKI, G.; PAULA, L.G.; FERREIRA ANTONELLO, I.C.; POLI-DE-FIGUEIREDO, C.E.; PINHEIRODA-COSTA, B.E. 2010. A Flow-mediated dilatation in the differential diagnosis of preeclampsia syndrome. Arq. Bras. Cardiol. 94(2):195-200. FLACK, J.M.; KEITH, C.; FERDINAND, K.C.; NASSER, S.A.; ROSSI, N.F. 2010. Hypertension in special populations: chronic kidney disease, organ transplant recipients, pregnancy, autonomic dysfunction, racial and ethnic Populations. Cardiol. Clin. 28(4):623-638. GARZÓN, D.; AGUDELO, C.C.; PARDO, R.; GAITÁN, H.; GÓMEZ, P.I.; PINILLA, A.R.; BUSTOS, J.C.; SÁNCHEZ, C.L.; PINEDA, F. 2010. Guia 14. Atencion de las complicaciones hipertensivas asociadas al embarazo. Ministerio de la Proteccion Social. Secretaria de Salud de Bogota. p.37-52. GRILL, S.; RUSTERHOLZ, C.; ZANETTI-DÄLLENBACH, R.; TERCANLI, S.; HOLZGREVE, W.; HAHN, S.; LAPAIRE, O. 2009. Potential markers of preeclampsia: a review. Reprod. Biol. Endocrin. 14:7-70. HAUTH, J.C.; EWELL, M.G.; LEVINE, R.J.; ESTERLITZ, J.R.; SIBAI, B.; CURET, L.B.; CATALANO, P.M.; MORRIS, C.D. 2000. Pregnancy outcomes in healthy nulliparas who developed hypertension. Calcium for Preeclampsia Prevention Study Group. Obstet. Gynecol. 95(1):24-28. HENRIQUES, A.C.; CARVALHO, F.H.; FEITOSA, H.N.; MACENA, R.H.; MOTA, R.M.; ALENCAR, J. 2014. Endothelial dysfunction after pregnancy induced hypertension. Int J Gynaecol Obstet 124(3):230-234. JAMES, P.R.; NELSON-PIERCY, C. 2004. Management of hypertension before, during, and after pregnancy. Heart. 90:1499-1504. LASH, G.E.; NARUSE, K.; ROBSON, A.; INNES, B.A.; SEARLE, R.F.; ROBSON, S.C.; BULMER, J.N. 2011. Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production. Hum. Reprod. 26(9):2289-2295. LATA, I. 2013. Hepatobiliary diseases during pregnancy and their management: An update. Int. J. Crit. Illn. In.j Sci. 3(3):175-182. 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