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spelling	A mediastinal small cell neuroendocrine carcinoma is a rare form of malignancy. Diagnosis requires imaging studies, pathological identification and immunohistochemistry markers. These tumors are aggressive and recurrence and metastases frequently complicate patient management. We present a case 78-year-old woman with complaints over 4 months of weight loss of four kilograms, cough and expectoration. Normal chest physical examination. History of smoking twenty pack-years. Chest X-ray showed a soft tissue density in the right border in region cardiomediastinun region. A computed tomography scan showed an infiltrative soft tissue in the right upper and middle mediastinum diameter of 4.9 x 4.7 x 7.4 centimeters involving major bronchovascular structures. The biopsy was performed by video thoracoscopy. Histologic analysis of the biopsies and inmunohistoquimical studies were positive for different markers and concluded small cell neuroendocrine carcinoma. Arciniegas Quiroga, William Arciniegas Grisales, Mateo Jaramillo Hurtado, Santiago neoplasia carcinoma neuroendocrino inmunohistoquimica neoplasia carcinoma neuroendocrino inmunohistoquimica 36 1 Artículo de revista Journal article 2024-06-07T00:00:00Z 2024-06-07T00:00:00Z 2024-06-07 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/692 10.30789/rcneumologia.v36.n1.2024.692 https://doi.org/10.30789/rcneumologia.v36.n1.2024.692 spa https://creativecommons.org/licenses/by-nc-sa/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0. 91 102 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/692/806 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	A mediastinal small cell neuroendocrine carcinoma is a rare form of malignancy. Diagnosis requires imaging studies, pathological identification and immunohistochemistry markers. These tumors are aggressive and recurrence and metastases frequently complicate patient management. We present a case 78-year-old woman with complaints over 4 months of weight loss of four kilograms, cough and expectoration. Normal chest physical examination. History of smoking twenty pack-years. Chest X-ray showed a soft tissue density in the right border in region cardiomediastinun region. A computed tomography scan showed an infiltrative soft tissue in the right upper and middle mediastinum diameter of 4.9 x 4.7 x 7.4 centimeters involving major bronchovascular structures. The biopsy was performed by video thoracoscopy. Histologic analysis of the biopsies and inmunohistoquimical studies were positive for different markers and concluded small cell neuroendocrine carcinoma.
author	Arciniegas Quiroga, William Arciniegas Grisales, Mateo Jaramillo Hurtado, Santiago
spellingShingle	Arciniegas Quiroga, William Arciniegas Grisales, Mateo Jaramillo Hurtado, Santiago neoplasia carcinoma neuroendocrino inmunohistoquimica neoplasia carcinoma neuroendocrino inmunohistoquimica
author_facet	Arciniegas Quiroga, William Arciniegas Grisales, Mateo Jaramillo Hurtado, Santiago
topic	neoplasia carcinoma neuroendocrino inmunohistoquimica neoplasia carcinoma neuroendocrino inmunohistoquimica
topic_facet	neoplasia carcinoma neuroendocrino inmunohistoquimica neoplasia carcinoma neuroendocrino inmunohistoquimica
topicspa_str_mv	neoplasia carcinoma neuroendocrino inmunohistoquimica
citationvolume	36
citationissue	1
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/692
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0. info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2024-06-07
date_accessioned	2024-06-07T00:00:00Z
date_available	2024-06-07T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/692
url_doi	https://doi.org/10.30789/rcneumologia.v36.n1.2024.692
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v36.n1.2024.692
citationstartpage	91
citationendpage	102
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/692/806
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