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spelling	Benign metastasizing leiomyomatosis (BML) is a rare condition, first described by Forkel in 1910, and at least 150 cases have been reported in the literature so far (1). It is caused by metastasis and proliferation of smooth muscle tissue from a uterine myoma. At the imaging level, it manifests with multiple nodules located most frequently in the lung, lymph nodes, peritoneum, bone, heart and skin. In symptomatic cases, they are usually taken to surgical resection, bilateral oophorectomy and/or hormonal inhibition, some cases being refractory. We present the case of a 51-year-old woman, who came for consultation due to a clinical picture of 2 years of evolution characterized by progressive dyspnea, associated with dry cough and chest pain. A history of hysterectomy for dysfunctional uterine bleeding 14 years ago was documented, and pathology report concluded a diagnosis of uterine leiomyomatosis. Chest CT scan revealed multiple non-calcified solid random pulmonary nodules. Samples obtained from the lung parenchyma were obtained by right thoracoscopy performing lateral segmental lobectomy of the middle lobe, with histopathological findings of mesenchymal proliferation, epithelial, and immunohistochemical markers compatible with metastatic leiomyomatosis. Moreno Carrillo, María Angélica Torres, María Carolina Saavedra, Alfredo Parra Medina, Rafael leiomyomatosis neoplasia lung pathology leiomiomatosis neoplasia pulmón patología 36 1 Artículo de revista Journal article 2024-06-07T00:00:00Z 2024-06-07T00:00:00Z 2024-06-07 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/690 10.30789/rcneumologia.v36.n1.2024.690 https://doi.org/10.30789/rcneumologia.v36.n1.2024.690 spa https://creativecommons.org/licenses/by-nc-sa/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0. 48 53 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/690/796 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	Benign metastasizing leiomyomatosis (BML) is a rare condition, first described by Forkel in 1910, and at least 150 cases have been reported in the literature so far (1). It is caused by metastasis and proliferation of smooth muscle tissue from a uterine myoma. At the imaging level, it manifests with multiple nodules located most frequently in the lung, lymph nodes, peritoneum, bone, heart and skin. In symptomatic cases, they are usually taken to surgical resection, bilateral oophorectomy and/or hormonal inhibition, some cases being refractory. We present the case of a 51-year-old woman, who came for consultation due to a clinical picture of 2 years of evolution characterized by progressive dyspnea, associated with dry cough and chest pain. A history of hysterectomy for dysfunctional uterine bleeding 14 years ago was documented, and pathology report concluded a diagnosis of uterine leiomyomatosis. Chest CT scan revealed multiple non-calcified solid random pulmonary nodules. Samples obtained from the lung parenchyma were obtained by right thoracoscopy performing lateral segmental lobectomy of the middle lobe, with histopathological findings of mesenchymal proliferation, epithelial, and immunohistochemical markers compatible with metastatic leiomyomatosis.
author	Moreno Carrillo, María Angélica Torres, María Carolina Saavedra, Alfredo Parra Medina, Rafael
spellingShingle	Moreno Carrillo, María Angélica Torres, María Carolina Saavedra, Alfredo Parra Medina, Rafael leiomyomatosis neoplasia lung pathology leiomiomatosis neoplasia pulmón patología
author_facet	Moreno Carrillo, María Angélica Torres, María Carolina Saavedra, Alfredo Parra Medina, Rafael
topic	leiomyomatosis neoplasia lung pathology leiomiomatosis neoplasia pulmón patología
topic_facet	leiomyomatosis neoplasia lung pathology leiomiomatosis neoplasia pulmón patología
topicspa_str_mv	leiomiomatosis neoplasia pulmón patología
citationvolume	36
citationissue	1
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/690
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0. info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2024-06-07
date_accessioned	2024-06-07T00:00:00Z
date_available	2024-06-07T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/690
url_doi	https://doi.org/10.30789/rcneumologia.v36.n1.2024.690
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v36.n1.2024.690
citationstartpage	48
citationendpage	53
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/690/796
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