Titulo:
.
Guardado en:
0121-5426
2538-9513
27
2016-10-05
Revista Colombiana de Neumología - 2016
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_69 |
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Introduction: Strongyloides stercoralis (Ss) is a parasite that causes severe infections, especially in immunocompromised patients; hyperinfection syndrome is one of its most serious manifestations. Early detection is vital for initiating adequate therapy. In this sense, bronchoscopy and bronchoalveolar lavage cytology are useful tools for early diagnosis.Patients and methods: retrospective review of cases of Ss hyperinfection syndrome diagnosed by bronchoalveolar lavage cytology at the Fundación Valle del Lili, Cali over the period from 2004 to 2012; 8 cases were found; we describe the demographic and clinical characteristics, risk factors, findings, and outcomes, and carry out a review of the literature.Results: 7 male (88%) and 1 female (12%) cases were found, the mean age was 48 years, 2 patients (22%) had HIV infection, 3 patients had chronically taken steroids (heart transplant, SLE nephritis, and chemotherapy) (33%), 2 patients were severely malnourished, 2 patients had positive human T-cell lymphotropic virus (HTLV-1). None of the patients had eosinophilia. All were treated with ivermectin and broad spectrum antibiotics in order to cover Gram-negative bacteremia (33% had positive cultures). In-hospital mortality was 62,5%.Conclusion: hyperinfection syndrome is a severe complication of Ss infection in immunocompromised patients. Despite great deterioration of the patient’s general condition, its clinical presentation is not specific. A high index of clinical suspicion is necessary for diagnosis and timely therapy. In these cases, bronchoalveolar lavage cytology is a useful tool form identifying the organism. Fernández, MD., Liliana González, MD., Alejandro Sua, MD., PhDc., Luz Fernanda Vargas, MD., Diego Muñoz, MD., Carlos Andrés strongyloidiasis bronchoalveolar lavage cytology hyperinfection syndrome Strongyloidiasis lavado broncoalveolar citología síndrome de hiperinfección 27 4 Artículo de revista Journal article 2016-10-05T22:12:32Z 2016-10-05T22:12:32Z 2016-10-05 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/69 10.30789/rcneumologia.v27.n4.2015.69 https://doi.org/10.30789/rcneumologia.v27.n4.2015.69 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/69/66 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Introduction: Strongyloides stercoralis (Ss) is a parasite that causes severe infections, especially in immunocompromised patients; hyperinfection syndrome is one of its most serious manifestations. Early detection is vital for initiating adequate therapy. In this sense, bronchoscopy and bronchoalveolar lavage cytology are useful tools for early diagnosis.Patients and methods: retrospective review of cases of Ss hyperinfection syndrome diagnosed by bronchoalveolar lavage cytology at the Fundación Valle del Lili, Cali over the period from 2004 to 2012; 8 cases were found; we describe the demographic and clinical characteristics, risk factors, findings, and outcomes, and carry out a review of the literature.Results: 7 male (88%) and 1 female (12%) cases were found, the mean age was 48 years, 2 patients (22%) had HIV infection, 3 patients had chronically taken steroids (heart transplant, SLE nephritis, and chemotherapy) (33%), 2 patients were severely malnourished, 2 patients had positive human T-cell lymphotropic virus (HTLV-1). None of the patients had eosinophilia. All were treated with ivermectin and broad spectrum antibiotics in order to cover Gram-negative bacteremia (33% had positive cultures). In-hospital mortality was 62,5%.Conclusion: hyperinfection syndrome is a severe complication of Ss infection in immunocompromised patients. Despite great deterioration of the patient’s general condition, its clinical presentation is not specific. A high index of clinical suspicion is necessary for diagnosis and timely therapy. In these cases, bronchoalveolar lavage cytology is a useful tool form identifying the organism.
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| author |
Fernández, MD., Liliana González, MD., Alejandro Sua, MD., PhDc., Luz Fernanda Vargas, MD., Diego Muñoz, MD., Carlos Andrés |
| spellingShingle |
Fernández, MD., Liliana González, MD., Alejandro Sua, MD., PhDc., Luz Fernanda Vargas, MD., Diego Muñoz, MD., Carlos Andrés strongyloidiasis bronchoalveolar lavage cytology hyperinfection syndrome Strongyloidiasis lavado broncoalveolar citología síndrome de hiperinfección |
| author_facet |
Fernández, MD., Liliana González, MD., Alejandro Sua, MD., PhDc., Luz Fernanda Vargas, MD., Diego Muñoz, MD., Carlos Andrés |
| topic |
strongyloidiasis bronchoalveolar lavage cytology hyperinfection syndrome Strongyloidiasis lavado broncoalveolar citología síndrome de hiperinfección |
| topic_facet |
strongyloidiasis bronchoalveolar lavage cytology hyperinfection syndrome Strongyloidiasis lavado broncoalveolar citología síndrome de hiperinfección |
| topicspa_str_mv |
Strongyloidiasis lavado broncoalveolar citología síndrome de hiperinfección |
| citationvolume |
27 |
| citationissue |
4 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/69 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
| type_coarversion |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2016-10-05 |
| date_accessioned |
2016-10-05T22:12:32Z |
| date_available |
2016-10-05T22:12:32Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/69 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v27.n4.2015.69 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v27.n4.2015.69 |
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https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/69/66 |
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1811200691265339392 |