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spelling	Background: Several studies about the hemodynamic effects of pressure support ventilation (PSV) have appeared over the past two years. These studies have been carried out on less than 15 patients, and none of them has compared the physiological effects of PSV and synchronized intermittent mandatory ventilation (SIMV) on the same patient. Objective: To establish the hemodynamic effects of PSV as compared with those of SIMV. Design: Prospective, controlled trial. Patients and methods: 31 patients were included in the study, from June 1993 to May 1995. They were distributed at random to be handled with SIMV or assist-control ventilation (ACV) during the stabilization phase. Before initiating the weaning, and after random assignation, the patients were put on PSV or SIMV for two hours (STEP 1), and hemodynamic and arteriovenous blood gas measurements were performed. Thereafter the patients were put on ACV for one hour and then to the other ventilation mode for two more hours (STEP 2), with new measurements performed. A 10cc/Kg variable, FIO2 of 40% and PEEP of 4 were maintained. The variables studied were pulmonary capillary pressure (W), central venous pressure (CVP), cardiac index (CI), oxygen supply (DOS), oxygen consumption (VO2), heart rate, systemic and pulmonary vascular resistances, arterial oxygen saturation (SaO2), and and lung distensibility (D). The results obtained from the total group (n=31) are presented thereafter on the two steps. We then divided this into two subgroups on the basis of the illness. Group 1: Systemic inflammatory response syndrome (SIRS): sepsis, ARDS, etc.) and Group 2: Severe cardiac failure (SCF). The statistical analysis was done with average, standard deviation (s), and the variables evaluated were analyzed by means of the Student Tos test (p&lt;0,05) Results: No fundamental differences were found among the 31 patients; the same occurred in the group of patients with SIRS, but when comparing the hemodynamics of the patients with SCF it was found that they had a better CI with PSV than with SIMV. The reason for this could be in that PSV reduces the preload, which could be of benefit in this type of patients. PSV reduces IVO2 because it facilitates ventilator/patient coupling. From the ventilatory point of view, improvedoxygenation was evident with PSV in all the groups. Conclusion: PSV may be considered the method of choice for the management of patients with SHF. Dueñas, Carmelo García Del Río, Carlos Carvajal, Martín Olmos Ruiz, Gloria Vélez, Patricia mechanical ventilation hemodynamic effects pressure support ventilation synchronized mandatory intermittent ventilation ventilación mecánica efectos hemodinámicos ventilación asistida por presión ventilación mandatoria intermitente sincronizada 22 4 Artículo de revista Journal article 2010-12-04T00:00:00Z 2010-12-04T00:00:00Z 2010-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/680 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/680 spa https://creativecommons.org/licenses/by-nc-nd/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0. 136 142 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/680/555 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	Background: Several studies about the hemodynamic effects of pressure support ventilation (PSV) have appeared over the past two years. These studies have been carried out on less than 15 patients, and none of them has compared the physiological effects of PSV and synchronized intermittent mandatory ventilation (SIMV) on the same patient. Objective: To establish the hemodynamic effects of PSV as compared with those of SIMV. Design: Prospective, controlled trial. Patients and methods: 31 patients were included in the study, from June 1993 to May 1995. They were distributed at random to be handled with SIMV or assist-control ventilation (ACV) during the stabilization phase. Before initiating the weaning, and after random assignation, the patients were put on PSV or SIMV for two hours (STEP 1), and hemodynamic and arteriovenous blood gas measurements were performed. Thereafter the patients were put on ACV for one hour and then to the other ventilation mode for two more hours (STEP 2), with new measurements performed. A 10cc/Kg variable, FIO2 of 40% and PEEP of 4 were maintained. The variables studied were pulmonary capillary pressure (W), central venous pressure (CVP), cardiac index (CI), oxygen supply (DOS), oxygen consumption (VO2), heart rate, systemic and pulmonary vascular resistances, arterial oxygen saturation (SaO2), and and lung distensibility (D). The results obtained from the total group (n=31) are presented thereafter on the two steps. We then divided this into two subgroups on the basis of the illness. Group 1: Systemic inflammatory response syndrome (SIRS): sepsis, ARDS, etc.) and Group 2: Severe cardiac failure (SCF). The statistical analysis was done with average, standard deviation (s), and the variables evaluated were analyzed by means of the Student Tos test (p&lt;0,05) Results: No fundamental differences were found among the 31 patients; the same occurred in the group of patients with SIRS, but when comparing the hemodynamics of the patients with SCF it was found that they had a better CI with PSV than with SIMV. The reason for this could be in that PSV reduces the preload, which could be of benefit in this type of patients. PSV reduces IVO2 because it facilitates ventilator/patient coupling. From the ventilatory point of view, improvedoxygenation was evident with PSV in all the groups. Conclusion: PSV may be considered the method of choice for the management of patients with SHF.
author	Dueñas, Carmelo García Del Río, Carlos Carvajal, Martín Olmos Ruiz, Gloria Vélez, Patricia
spellingShingle	Dueñas, Carmelo García Del Río, Carlos Carvajal, Martín Olmos Ruiz, Gloria Vélez, Patricia mechanical ventilation hemodynamic effects pressure support ventilation synchronized mandatory intermittent ventilation ventilación mecánica efectos hemodinámicos ventilación asistida por presión ventilación mandatoria intermitente sincronizada
author_facet	Dueñas, Carmelo García Del Río, Carlos Carvajal, Martín Olmos Ruiz, Gloria Vélez, Patricia
topic	mechanical ventilation hemodynamic effects pressure support ventilation synchronized mandatory intermittent ventilation ventilación mecánica efectos hemodinámicos ventilación asistida por presión ventilación mandatoria intermitente sincronizada
topic_facet	mechanical ventilation hemodynamic effects pressure support ventilation synchronized mandatory intermittent ventilation ventilación mecánica efectos hemodinámicos ventilación asistida por presión ventilación mandatoria intermitente sincronizada
topicspa_str_mv	ventilación mecánica efectos hemodinámicos ventilación asistida por presión ventilación mandatoria intermitente sincronizada
citationvolume	22
citationissue	4
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/680
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-nd/4.0 Revista Colombiana de Neumología - 2023 Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0. info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2010-12-04
date_accessioned	2010-12-04T00:00:00Z
date_available	2010-12-04T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/680
url_doi	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/680
issn	0121-5426
eissn	2538-9513
citationstartpage	136
citationendpage	142
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/680/555
_version_	1811200733201039360

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