id	metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_679
record_format	ojs
spelling	Some studies have suggested a correlation between eosinophils and greater severity, poorer control of asthma, poorer indexes of lung function, and greater bronchial hyperreactivity as measured by the metacholine challenge test. However, we do not know the behavior of this correlation in Colombia or in the asthma clinic of Hospital San Ignacio. Currently, Wright staining of sputum is interpreted only in the light of the presence of neutrophils, disregarding the value of eosinophils. Methods: An observational, descriptive, concordance study was carried out over a period of one year, with patients aged 15 years or older, who were admitted through the emergency department with asthmatic crises requiring hospitalization. Severity of the crisis, severity of eosinophils in blood and sputum, peak expiratory flow, duration of hospital stay (in main ward or in ICU), and need for mechanical ventilation were determined in order to define whether there was a correlation between the severity of these variables as predictors of the severity of the asthmatic crisis. Results: A total number of 169 patients were included, with an age average of 43.3 years, predominantly women (84%), of whom 56.8% were classified as severe and 43.2% as moderate asthmatic crisis. The average of eosinophils in sputum was 17.2% and inblood 375.5 cells per cubic meter. Average length of hospital stay was 4.7 days, 0.5 days in the ICU (only 20 patients required ICU), and 0.2 days on mechanical ventilation. The count of eosinophils in blood was within normal values or highly increased in most patients; most of the patients had slight eosinophilia in sputum.PEF on admission was, on average, 40% of the optimal. The concordance observed between sputum and blood eosinophils was modest. No correlation was found between severity determined by eosinophils in sputum or blood and length of hospital stay, PEF, or drugs received. Conclusion: There is no correlation between the levels of eosinophilia found in sputum or blood and the severity of the crisis measured by number of days of hospital stay, days on mechanical ventilation, or value of peak expiratory flow. García Calderón, Clara Patricia Bermúdez, Mary Eosinophils severity asthma crisis eosinófilos severidad asma crisis 22 4 Artículo de revista Journal article 2010-12-04T00:00:00Z 2010-12-04T00:00:00Z 2010-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/679 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/679 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ 127 135 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/679/554 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	Some studies have suggested a correlation between eosinophils and greater severity, poorer control of asthma, poorer indexes of lung function, and greater bronchial hyperreactivity as measured by the metacholine challenge test. However, we do not know the behavior of this correlation in Colombia or in the asthma clinic of Hospital San Ignacio. Currently, Wright staining of sputum is interpreted only in the light of the presence of neutrophils, disregarding the value of eosinophils. Methods: An observational, descriptive, concordance study was carried out over a period of one year, with patients aged 15 years or older, who were admitted through the emergency department with asthmatic crises requiring hospitalization. Severity of the crisis, severity of eosinophils in blood and sputum, peak expiratory flow, duration of hospital stay (in main ward or in ICU), and need for mechanical ventilation were determined in order to define whether there was a correlation between the severity of these variables as predictors of the severity of the asthmatic crisis. Results: A total number of 169 patients were included, with an age average of 43.3 years, predominantly women (84%), of whom 56.8% were classified as severe and 43.2% as moderate asthmatic crisis. The average of eosinophils in sputum was 17.2% and inblood 375.5 cells per cubic meter. Average length of hospital stay was 4.7 days, 0.5 days in the ICU (only 20 patients required ICU), and 0.2 days on mechanical ventilation. The count of eosinophils in blood was within normal values or highly increased in most patients; most of the patients had slight eosinophilia in sputum.PEF on admission was, on average, 40% of the optimal. The concordance observed between sputum and blood eosinophils was modest. No correlation was found between severity determined by eosinophils in sputum or blood and length of hospital stay, PEF, or drugs received. Conclusion: There is no correlation between the levels of eosinophilia found in sputum or blood and the severity of the crisis measured by number of days of hospital stay, days on mechanical ventilation, or value of peak expiratory flow.
author	García Calderón, Clara Patricia Bermúdez, Mary
spellingShingle	García Calderón, Clara Patricia Bermúdez, Mary Eosinophils severity asthma crisis eosinófilos severidad asma crisis
author_facet	García Calderón, Clara Patricia Bermúdez, Mary
topic	Eosinophils severity asthma crisis eosinófilos severidad asma crisis
topic_facet	Eosinophils severity asthma crisis eosinófilos severidad asma crisis
topicspa_str_mv	eosinófilos severidad asma crisis
citationvolume	22
citationissue	4
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/679
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2010-12-04
date_accessioned	2010-12-04T00:00:00Z
date_available	2010-12-04T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/679
url_doi	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/679
issn	0121-5426
eissn	2538-9513
citationstartpage	127
citationendpage	135
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/679/554
_version_	1811200733099327488

.

Código QR

Estadísticas y Métricas Alternativas

Títulos similares