id	metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_678
record_format	ojs
spelling	Objective: to determine whether orally administered corticosteroids are more effective and less costly than intravenous corticosteroids for the management of moderate or severe asthmatic crises. Design: a cost-minimization study was performed using decision analysis. Materials and methods: the study was carried out at Hospital Universitario de San Ignacio of Bogotá (Colombia), a privately owned, third level institution. Determination of costs and resources utilized was done by reviewing the clinicahistories of patients with asthma who received care over the period 1988-1997. A projection was done for 1.000 subjects receiving care for that ailment. Determination of the effectiveness or oral vs. intravenous corticosteroids wasbased on a meta-analysis. Results: the patients received, on average, 4 days of therapy with intravenous corticosteroids; the cost of this medication for 1.000 persons is thus $ 148.404.000, whereas the cost of oral prednisolone or its equivalent at 1 mg/kg/day would have been $ 8.493.000 (5,7%). Two meta-analyses found in the literature demonstrated that the activity of oral and intravenous corticosteroids was similar, and that, unless there is some contraindication for oral administration, the effects on the patients are also similar. Conclusions: since the efficacy of oral corticosteroids is similar to that of intravenous corticosteroids in the management of asthmatic crises, and since the cost of oral therapy is much lower, it is recommended that patients should receive therapy with oral corticosteroids, except when the oral route is contraindicated Londoño Trujillo, Darío Caicedo, Mónica Patricia Bermúdez Gómez, Mary Dennis Verano, Rodolfo J. Lobelo, Rafael Roa Buitrago, Jairo H. Solarte Rodríguez, Iván asthma asthmatic crisis oral corticosteroids intravenous corticosteroids costs cost-minimization asma crisis asmática corticosteroides orales corticosteroides endovenosos costos minimización de costos 22 4 Artículo de revista Journal article 2010-12-04T00:00:00Z 2010-12-04T00:00:00Z 2010-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/678 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/678 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ 122 126 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/678/553 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	Objective: to determine whether orally administered corticosteroids are more effective and less costly than intravenous corticosteroids for the management of moderate or severe asthmatic crises. Design: a cost-minimization study was performed using decision analysis. Materials and methods: the study was carried out at Hospital Universitario de San Ignacio of Bogotá (Colombia), a privately owned, third level institution. Determination of costs and resources utilized was done by reviewing the clinicahistories of patients with asthma who received care over the period 1988-1997. A projection was done for 1.000 subjects receiving care for that ailment. Determination of the effectiveness or oral vs. intravenous corticosteroids wasbased on a meta-analysis. Results: the patients received, on average, 4 days of therapy with intravenous corticosteroids; the cost of this medication for 1.000 persons is thus $ 148.404.000, whereas the cost of oral prednisolone or its equivalent at 1 mg/kg/day would have been $ 8.493.000 (5,7%). Two meta-analyses found in the literature demonstrated that the activity of oral and intravenous corticosteroids was similar, and that, unless there is some contraindication for oral administration, the effects on the patients are also similar. Conclusions: since the efficacy of oral corticosteroids is similar to that of intravenous corticosteroids in the management of asthmatic crises, and since the cost of oral therapy is much lower, it is recommended that patients should receive therapy with oral corticosteroids, except when the oral route is contraindicated
author	Londoño Trujillo, Darío Caicedo, Mónica Patricia Bermúdez Gómez, Mary Dennis Verano, Rodolfo J. Lobelo, Rafael Roa Buitrago, Jairo H. Solarte Rodríguez, Iván
spellingShingle	Londoño Trujillo, Darío Caicedo, Mónica Patricia Bermúdez Gómez, Mary Dennis Verano, Rodolfo J. Lobelo, Rafael Roa Buitrago, Jairo H. Solarte Rodríguez, Iván asthma asthmatic crisis oral corticosteroids intravenous corticosteroids costs cost-minimization asma crisis asmática corticosteroides orales corticosteroides endovenosos costos minimización de costos
author_facet	Londoño Trujillo, Darío Caicedo, Mónica Patricia Bermúdez Gómez, Mary Dennis Verano, Rodolfo J. Lobelo, Rafael Roa Buitrago, Jairo H. Solarte Rodríguez, Iván
topic	asthma asthmatic crisis oral corticosteroids intravenous corticosteroids costs cost-minimization asma crisis asmática corticosteroides orales corticosteroides endovenosos costos minimización de costos
topic_facet	asthma asthmatic crisis oral corticosteroids intravenous corticosteroids costs cost-minimization asma crisis asmática corticosteroides orales corticosteroides endovenosos costos minimización de costos
topicspa_str_mv	asma crisis asmática corticosteroides orales corticosteroides endovenosos costos minimización de costos
citationvolume	22
citationissue	4
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/678
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2010-12-04
date_accessioned	2010-12-04T00:00:00Z
date_available	2010-12-04T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/678
url_doi	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/678
issn	0121-5426
eissn	2538-9513
citationstartpage	122
citationendpage	126
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/678/553
_version_	1811200733008101376

.

Código QR

Estadísticas y Métricas Alternativas

Títulos similares