Titulo:
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Guardado en:
0121-5426
2538-9513
34
2022-06-01
39
45
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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Pulmonary Aspergillosis has classically been considered a disease of immunocompromised patients (hematological neoplasms, severe neutropenia, solid organ transplantation, human immunodeficiency virus / acquired immunodeficiency syndrome HIV / AIDS) or immunocompetent but critically ill patients. However, during the COVID-19 pandemic the behavior of fungal infections has changed, being observed more frequently today. A case of 20-year-old male patient, from San Andrés islands, north of Colombia; With no known prior pathology, he was admitted to the emergency department with a 3-day fever and dry cough. On admission, a conscious patient with fluctuating attention, tachycardia and fever. Pulmonary and abdominal examination without alterations. Paraclinical patients with leukocytosis, neutrophilia, rapid test for covid19 negative and NS1 for dengue negative. The chest X-ray in lateral projection shows interstitial infiltrates and in tomography as nodular lesions with poorly defined edges, some spiculated, with neighboring interstitial infiltrate (tumor or infectious deposits). A positive SARS COV 2 RT-PCR result, due to radiological findings, a lung biopsy was performed by thoracoscopy, the histological study of which revealed multiple nodules fungal structures inside compatible with aspergillus. First-line therapy with voriconazole was started, asymptomatic discharge upon completion of treatment. As conclusion fungal infections represent a diagnostic challenge, their delay, due to lack of suspicion in the immunocompetent patient, impacts morbidity and mortality. The increase in fungal infections during the COVID-19 pandemic makes it necessary to consider aspergillosis as a differential diagnosis in a patient with COVID-19, with persistent fever and atypical radiological findings. Medina Ahumada, Patricia Borre-Naranjo, Diana Martínez Duran, Analida Yovana Herrera, Sandra Castro-Mendoza, William Baños, Ivan coinfection aspergillus pulmonary aspergillosis coinfección aspergillus COVID-19 aspergilosis pulmonar 34 1 Artículo de revista Journal article 2022-06-01T00:00:00Z 2022-06-01T00:00:00Z 2022-06-01 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/557 10.30789/rcneumologia.v34.n1.2022.557 https://doi.org/10.30789/rcneumologia.v34.n1.2022.557 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ 39 45 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/557/508 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Pulmonary Aspergillosis has classically been considered a disease of immunocompromised patients (hematological neoplasms, severe neutropenia, solid organ transplantation, human immunodeficiency virus / acquired immunodeficiency syndrome HIV / AIDS) or immunocompetent but critically ill patients. However, during the COVID-19 pandemic the behavior of fungal infections has changed, being observed more frequently today.
A case of 20-year-old male patient, from San Andrés islands, north of Colombia; With no known prior pathology, he was admitted to the emergency department with a 3-day fever and dry cough. On admission, a conscious patient with fluctuating attention, tachycardia and fever. Pulmonary and abdominal examination without alterations. Paraclinical patients with leukocytosis, neutrophilia, rapid test for covid19 negative and NS1 for dengue negative. The chest X-ray in lateral projection shows interstitial infiltrates and in tomography as nodular lesions with poorly defined edges, some spiculated, with neighboring interstitial infiltrate (tumor or infectious deposits). A positive SARS COV 2 RT-PCR result, due to radiological findings, a lung biopsy was performed by thoracoscopy, the histological study of which revealed multiple nodules fungal structures inside compatible with aspergillus. First-line therapy with voriconazole was started, asymptomatic discharge upon completion of treatment. As conclusion fungal infections represent a diagnostic challenge, their delay, due to lack of suspicion in the immunocompetent patient, impacts morbidity and mortality. The increase in fungal infections during the COVID-19 pandemic makes it necessary to consider aspergillosis as a differential diagnosis in a patient with COVID-19, with persistent fever and atypical radiological findings.
|
| author |
Medina Ahumada, Patricia Borre-Naranjo, Diana Martínez Duran, Analida Yovana Herrera, Sandra Castro-Mendoza, William Baños, Ivan |
| spellingShingle |
Medina Ahumada, Patricia Borre-Naranjo, Diana Martínez Duran, Analida Yovana Herrera, Sandra Castro-Mendoza, William Baños, Ivan coinfection aspergillus pulmonary aspergillosis coinfección aspergillus COVID-19 aspergilosis pulmonar |
| author_facet |
Medina Ahumada, Patricia Borre-Naranjo, Diana Martínez Duran, Analida Yovana Herrera, Sandra Castro-Mendoza, William Baños, Ivan |
| topic |
coinfection aspergillus pulmonary aspergillosis coinfección aspergillus COVID-19 aspergilosis pulmonar |
| topic_facet |
coinfection aspergillus pulmonary aspergillosis coinfección aspergillus COVID-19 aspergilosis pulmonar |
| topicspa_str_mv |
coinfección aspergillus COVID-19 aspergilosis pulmonar |
| citationvolume |
34 |
| citationissue |
1 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/557 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2022-06-01 |
| date_accessioned |
2022-06-01T00:00:00Z |
| date_available |
2022-06-01T00:00:00Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/557 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v34.n1.2022.557 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v34.n1.2022.557 |
| citationstartpage |
39 |
| citationendpage |
45 |
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https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/557/508 |
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