id	metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_327
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spelling	INTRODUCTION: Tuberculosis (TBC) continues to be a global public health problem. Despite advances in treatment, it has been shown that patient’s nutritional status influences the prognosis and results of treatment. The objective of this study was to describe the nutri- tional status, diagnosis and results of treatment in patients with TBC.MATERIALS AND METHODS: Historic cohort study. We analyzed adult patients older than 18 years with TBC and weight and height record at the time of diagnosis between Fe- bruary 2007 to May 2017 at Fundación Valle del Lili (FVL) in Cali, Colombia.RESULTS AND DISCUSSION: A total of 388 patients were included, 52% (n=200) had normal weight and 23% (n=88) had low weight. The most frequent comorbidities were human immunodeficiency virus (HIV) in 14% (n=56) and diabetes mellitus in 13% (n=52). There was no statistically significant association between body mass index (BMI) and albumin level (p: 0.387, Odds ratio [OR]: 1.29; confidence interval [CI] 95%: 0.73-2.28). An overall mortality of 9% was found (n=35). BMI &lt;18.5 was not associated with mortality (p=0.65, OR: 0.81, CI 95%: 0.32-2.07). In more than 50% of the patients, hypoalbuminemia was documented at the time of diagnosis, which was associated with mortality (p &lt;0.001, OR: 6.23, CI 95%: 3.7-70.6).CONCLUSIONS: Knowing accurately the nutritional status of the patient with TBC could help to create strategies that allow to improve the prognosis and the results to treatment. BMI does not always reflect the actual nutritional status of the patient. The serum albumin level &lt;3.5 g/dL is a predictive marker of mortality in patients with active TBC disease. Moreno Soto, Karen Juliana Montaño Rivas, Isabella Parra Lara, Luis Gabriel Pacheco, Robinson García Goez, José Fernando Mycobacterium tuberculosis nutritional status body mass index serum albumin mortality Mycobacterium tuberculosis estado nutricional índice de masa corporal albúmina sérica mortalidad 31 1 Artículo de revista Journal article 2019-08-15T00:00:00Z 2019-08-15T00:00:00Z 2019-08-15 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/327 10.30789/rcneumologia.v31.n1.2019.327 https://doi.org/10.30789/rcneumologia.v31.n1.2019.327 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2019 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/327/273 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	INTRODUCTION: Tuberculosis (TBC) continues to be a global public health problem. Despite advances in treatment, it has been shown that patient’s nutritional status influences the prognosis and results of treatment. The objective of this study was to describe the nutri- tional status, diagnosis and results of treatment in patients with TBC.MATERIALS AND METHODS: Historic cohort study. We analyzed adult patients older than 18 years with TBC and weight and height record at the time of diagnosis between Fe- bruary 2007 to May 2017 at Fundación Valle del Lili (FVL) in Cali, Colombia.RESULTS AND DISCUSSION: A total of 388 patients were included, 52% (n=200) had normal weight and 23% (n=88) had low weight. The most frequent comorbidities were human immunodeficiency virus (HIV) in 14% (n=56) and diabetes mellitus in 13% (n=52). There was no statistically significant association between body mass index (BMI) and albumin level (p: 0.387, Odds ratio [OR]: 1.29; confidence interval [CI] 95%: 0.73-2.28). An overall mortality of 9% was found (n=35). BMI &lt;18.5 was not associated with mortality (p=0.65, OR: 0.81, CI 95%: 0.32-2.07). In more than 50% of the patients, hypoalbuminemia was documented at the time of diagnosis, which was associated with mortality (p &lt;0.001, OR: 6.23, CI 95%: 3.7-70.6).CONCLUSIONS: Knowing accurately the nutritional status of the patient with TBC could help to create strategies that allow to improve the prognosis and the results to treatment. BMI does not always reflect the actual nutritional status of the patient. The serum albumin level &lt;3.5 g/dL is a predictive marker of mortality in patients with active TBC disease.
author	Moreno Soto, Karen Juliana Montaño Rivas, Isabella Parra Lara, Luis Gabriel Pacheco, Robinson García Goez, José Fernando
spellingShingle	Moreno Soto, Karen Juliana Montaño Rivas, Isabella Parra Lara, Luis Gabriel Pacheco, Robinson García Goez, José Fernando Mycobacterium tuberculosis nutritional status body mass index serum albumin mortality Mycobacterium tuberculosis estado nutricional índice de masa corporal albúmina sérica mortalidad
author_facet	Moreno Soto, Karen Juliana Montaño Rivas, Isabella Parra Lara, Luis Gabriel Pacheco, Robinson García Goez, José Fernando
topic	Mycobacterium tuberculosis nutritional status body mass index serum albumin mortality Mycobacterium tuberculosis estado nutricional índice de masa corporal albúmina sérica mortalidad
topic_facet	Mycobacterium tuberculosis nutritional status body mass index serum albumin mortality Mycobacterium tuberculosis estado nutricional índice de masa corporal albúmina sérica mortalidad
topicspa_str_mv	Mycobacterium tuberculosis estado nutricional índice de masa corporal albúmina sérica mortalidad
citationvolume	31
citationissue	1
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/327
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2019 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2019-08-15
date_accessioned	2019-08-15T00:00:00Z
date_available	2019-08-15T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/327
url_doi	https://doi.org/10.30789/rcneumologia.v31.n1.2019.327
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v31.n1.2019.327
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/327/273
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