id	metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_315
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spelling	INTRODUCTION: Alveolar hypoventilation is an alteration that leads to retention of carbon dioxide (CO2) and alteration in blood pressure of CO2 (PaCO2) due to multiple causes (hypoventilation syndromes). The diagnosis is with resting daytime blood gasometry with possible use of other tests such as the measurement of transcutaneous carbon dioxide (TcCO2).The diagnostic strategy is not yet fully defined, so our objective was to evaluate the prevalence of hypoventilation during sleep using different diagnostic criteria.MATERIALS AND METHODS: Observational, descriptive, retrospective, cross-sectional study of patients who required po- lysomnography between 2015 and 2016 with measurement of TcCO2 at the National Institute of Respiratory Diseases Ismael Cosio Villegas of Mexico City. Six different criteria of hypoventilation were applied during sleep. Three groups were established (withoutrespiratory disorders during sleep, patients with hypoventilation-obesity syndrome and patients with hypoventilation related to medi- cal-neuromuscular disorder). Patients who had no established diagnosis were excluded. The SenTec Digital Monitoring System was used to measure the TcCO2, obtaining baseline CO2, average CO2, maximum CO2 and CO2 time. The software SPSS v23 was used.The description was made with mean, median, standard deviation and percentages according to the type of variable. Concordancetests were performed between the different criteria applied for each distribution. Statistical significance was accepted when p &lt;0.05.RESULTS: A total sample of 143 patients. 51 without respiratory disorders during sleep, 63 with hypoventilation-obesity syn- drome and 29 with hypoventilation related to medical disorders (neuromuscular). The male gender predominated and they were young adults. A TcCO2 &gt;38 mm Hg is diagnosed in 68% of patients with hypoventilation-obesity syndrome and 69% of patientswith alveolar hypoventilation due to neuromuscular diseases (Cohen’s Kappa = 0.40). A TcCO2 &gt;49 mm Hg at night diagnosed 82%of patients with hypoventilation-obesity syndrome and 58% of patients with alveolar hypoventilation due to neuromuscular diseases(Cohen’s Kappa = 0.63).CONCLUSION: In the population studied, a peak of TcCO2 ≥49 mm Hg has a good degree according to the current diagnosis of the patient. Díaz Santos, Germán Domínguez, Héctor Daniel Guerrero Zúñiga, Selene Alveolar hypoventilation hypoventilation syndromes transcutaneous carbon dioxide hypoventilation during sleep síndromes de hipoventilación hipoventilación alveolar dióxido de carbono transcutáneo hipoventilación durante el sueño 30 2 Artículo de revista Journal article 2019-08-15T00:00:00Z 2019-08-15T00:00:00Z 2019-08-15 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/315 10.30789/rcneumologia.v30.n2.2018.315 https://doi.org/10.30789/rcneumologia.v30.n2.2018.315 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2019 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/315/261 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	INTRODUCTION: Alveolar hypoventilation is an alteration that leads to retention of carbon dioxide (CO2) and alteration in blood pressure of CO2 (PaCO2) due to multiple causes (hypoventilation syndromes). The diagnosis is with resting daytime blood gasometry with possible use of other tests such as the measurement of transcutaneous carbon dioxide (TcCO2).The diagnostic strategy is not yet fully defined, so our objective was to evaluate the prevalence of hypoventilation during sleep using different diagnostic criteria.MATERIALS AND METHODS: Observational, descriptive, retrospective, cross-sectional study of patients who required po- lysomnography between 2015 and 2016 with measurement of TcCO2 at the National Institute of Respiratory Diseases Ismael Cosio Villegas of Mexico City. Six different criteria of hypoventilation were applied during sleep. Three groups were established (withoutrespiratory disorders during sleep, patients with hypoventilation-obesity syndrome and patients with hypoventilation related to medi- cal-neuromuscular disorder). Patients who had no established diagnosis were excluded. The SenTec Digital Monitoring System was used to measure the TcCO2, obtaining baseline CO2, average CO2, maximum CO2 and CO2 time. The software SPSS v23 was used.The description was made with mean, median, standard deviation and percentages according to the type of variable. Concordancetests were performed between the different criteria applied for each distribution. Statistical significance was accepted when p &lt;0.05.RESULTS: A total sample of 143 patients. 51 without respiratory disorders during sleep, 63 with hypoventilation-obesity syn- drome and 29 with hypoventilation related to medical disorders (neuromuscular). The male gender predominated and they were young adults. A TcCO2 &gt;38 mm Hg is diagnosed in 68% of patients with hypoventilation-obesity syndrome and 69% of patientswith alveolar hypoventilation due to neuromuscular diseases (Cohen’s Kappa = 0.40). A TcCO2 &gt;49 mm Hg at night diagnosed 82%of patients with hypoventilation-obesity syndrome and 58% of patients with alveolar hypoventilation due to neuromuscular diseases(Cohen’s Kappa = 0.63).CONCLUSION: In the population studied, a peak of TcCO2 ≥49 mm Hg has a good degree according to the current diagnosis of the patient.
author	Díaz Santos, Germán Domínguez, Héctor Daniel Guerrero Zúñiga, Selene
spellingShingle	Díaz Santos, Germán Domínguez, Héctor Daniel Guerrero Zúñiga, Selene Alveolar hypoventilation hypoventilation syndromes transcutaneous carbon dioxide hypoventilation during sleep síndromes de hipoventilación hipoventilación alveolar dióxido de carbono transcutáneo hipoventilación durante el sueño
author_facet	Díaz Santos, Germán Domínguez, Héctor Daniel Guerrero Zúñiga, Selene
topic	Alveolar hypoventilation hypoventilation syndromes transcutaneous carbon dioxide hypoventilation during sleep síndromes de hipoventilación hipoventilación alveolar dióxido de carbono transcutáneo hipoventilación durante el sueño
topic_facet	Alveolar hypoventilation hypoventilation syndromes transcutaneous carbon dioxide hypoventilation during sleep síndromes de hipoventilación hipoventilación alveolar dióxido de carbono transcutáneo hipoventilación durante el sueño
topicspa_str_mv	síndromes de hipoventilación hipoventilación alveolar dióxido de carbono transcutáneo hipoventilación durante el sueño
citationvolume	30
citationissue	2
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/315
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2019 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2019-08-15
date_accessioned	2019-08-15T00:00:00Z
date_available	2019-08-15T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/315
url_doi	https://doi.org/10.30789/rcneumologia.v30.n2.2018.315
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v30.n2.2018.315
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/315/261
_version_	1811200708372856832

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