Titulo:
.
Guardado en:
0121-5426
2538-9513
29
2017-08-01
19
25
Revista Colombiana de Neumología - 2017
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_234 |
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ojs |
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Introduction: people older than 80 years are vulnerable to the development of tuberculosis; this is due to immunosenescence, comorbidities, malnutrition, and sedentariness, which predispose to primary infection or reactivation of latent infection. Its clinical presentation is unusual. Treatment of tuberculosis is difficult due to adverse events and drug interactions. Objective: to describe the clinical and microbiological characteristics and the most common outcomes of patients older than 80 years diagnosed with tuberculosis. Materials and methods: retrospective cohort study of patients older than 80 years diagnosed with tuberculosis. Information (clinical, microbiological, radiological, and regarding outcomes and response to treatment) from the institutional tuberculosis database was collected and analyzed. Results: between 2011 and 2016, 27 patients older than 80 years were diagnosed with tuberculosis. The median age was 84 years (IR 80-91); the following risk factors for this disease were identified: chronic obstructive pulmonary disease in 37%, tobacco use in 26%, diabetes in 11%, cancer in 11%, and previous infection by tuberculosis in 7%. Diagnosis was delayed (>30 days) in 74%. The sites of infection were: 52% pulmonary, 26% extrapulmonary, and 22% mixed. Of the patients with pulmonary involvement, 41% had positive sputum examinations and 50% had lung cavitations on chest radiographs. After treatment, tuberculosis was reported to be cured in 37%, death was reported in 15%, and follow-up was lost in 37%. Conclusions: there is evidence of delayed diagnosis, due to the fact that clinical and radiological presentation of tuberculosis in this age group is unusual with regard to the general population. Extrapulmonary tuberculosis was more common in older patients. The low rates of successful treatment, the high percentage of mortality, and the loss of follow-up are a challenge for the healthcare systems and professionals. García-Goez, José Fernando Esteban Munévar, Hernán Pacheco, Robinson older patient octogenarian tuberculosis antituberculous adulto mayor octogenario tuberculosis antituberculoso 29 1 Artículo de revista Journal article 2017-08-01T00:00:00Z 2017-08-01T00:00:00Z 2017-08-01 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/234 10.30789/rcneumologia.v29.n1.2017.234 https://doi.org/10.30789/rcneumologia.v29.n1.2017.234 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 19 25 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/234/219 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Introduction: people older than 80 years are vulnerable to the development of tuberculosis; this is due to immunosenescence, comorbidities, malnutrition, and sedentariness, which predispose to primary infection or reactivation of latent infection. Its clinical presentation is unusual. Treatment of tuberculosis is difficult due to adverse events and drug interactions. Objective: to describe the clinical and microbiological characteristics and the most common outcomes of patients older than 80 years diagnosed with tuberculosis. Materials and methods: retrospective cohort study of patients older than 80 years diagnosed with tuberculosis. Information (clinical, microbiological, radiological, and regarding outcomes and response to treatment) from the institutional tuberculosis database was collected and analyzed. Results: between 2011 and 2016, 27 patients older than 80 years were diagnosed with tuberculosis. The median age was 84 years (IR 80-91); the following risk factors for this disease were identified: chronic obstructive pulmonary disease in 37%, tobacco use in 26%, diabetes in 11%, cancer in 11%, and previous infection by tuberculosis in 7%. Diagnosis was delayed (>30 days) in 74%. The sites of infection were: 52% pulmonary, 26% extrapulmonary, and 22% mixed. Of the patients with pulmonary involvement, 41% had positive sputum examinations and 50% had lung cavitations on chest radiographs. After treatment, tuberculosis was reported to be cured in 37%, death was reported in 15%, and follow-up was lost in 37%. Conclusions: there is evidence of delayed diagnosis, due to the fact that clinical and radiological presentation of tuberculosis in this age group is unusual with regard to the general population. Extrapulmonary tuberculosis was more common in older patients. The low rates of successful treatment, the high percentage of mortality, and the loss of follow-up are a challenge for the healthcare systems and professionals.
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| author |
García-Goez, José Fernando Esteban Munévar, Hernán Pacheco, Robinson |
| spellingShingle |
García-Goez, José Fernando Esteban Munévar, Hernán Pacheco, Robinson older patient octogenarian tuberculosis antituberculous adulto mayor octogenario tuberculosis antituberculoso |
| author_facet |
García-Goez, José Fernando Esteban Munévar, Hernán Pacheco, Robinson |
| topic |
older patient octogenarian tuberculosis antituberculous adulto mayor octogenario tuberculosis antituberculoso |
| topic_facet |
older patient octogenarian tuberculosis antituberculous adulto mayor octogenario tuberculosis antituberculoso |
| topicspa_str_mv |
adulto mayor octogenario tuberculosis antituberculoso |
| citationvolume |
29 |
| citationissue |
1 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/234 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
| type_driver |
info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2017-08-01 |
| date_accessioned |
2017-08-01T00:00:00Z |
| date_available |
2017-08-01T00:00:00Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/234 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v29.n1.2017.234 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v29.n1.2017.234 |
| citationstartpage |
19 |
| citationendpage |
25 |
| url2_str_mv |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/234/219 |
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1811200705048870912 |