Titulo:
.
Guardado en:
0121-5426
2538-9513
24
2017-05-29
97
101
Revista Colombiana de Neumología - 2017
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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ojs |
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Some antineoplastic agents can cause pulmonary toxicity, according to their action profile. Bleomycin is one of the drugs with which this event has been reported. This cytostatic can injure the pulmonary endothelium and the alveolar epithelium, which can lead to an inflammatory and fibrotic process of the interstice with potentially fatal repercussions.The pathophysiology of the pulmonary lnjury is not fully understood, and therefore the potential molecular targets for prevention and treatment have not been defined. The only available treatment with possible clinical efficacy is early administration of corticoids, in order to prevent acule respiratory failure and pulmonary fibrosis. Galindo Pedraza, MD., Javier Leonardo García-Herreros Ochoa, MD., FCCP., Plutarco Saavedra Rodríguez, MD., Alfredo Sánchez Morales, MD., Edgar Alberto bleomycin pulmonary toxicity pulmonary fibrosis bleomicina toxicidad pulmonar fibrosis pulmonar 24 2 Artículo de revista Journal article 2017-05-29T21:41:51Z 2017-05-29T21:41:51Z 2017-05-29 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/190 10.30789/rcneumologia.v24.n2.2012.190 https://doi.org/10.30789/rcneumologia.v24.n2.2012.190 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 97 101 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/190/179 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Some antineoplastic agents can cause pulmonary toxicity, according to their action profile. Bleomycin is one of the drugs with which this event has been reported. This cytostatic can injure the pulmonary endothelium and the alveolar epithelium, which can lead to an inflammatory and fibrotic process of the interstice with potentially fatal repercussions.The pathophysiology of the pulmonary lnjury is not fully understood, and therefore the potential molecular targets for prevention and treatment have not been defined. The only available treatment with possible clinical efficacy is early administration of corticoids, in order to prevent acule respiratory failure and pulmonary fibrosis.
|
| author |
Galindo Pedraza, MD., Javier Leonardo García-Herreros Ochoa, MD., FCCP., Plutarco Saavedra Rodríguez, MD., Alfredo Sánchez Morales, MD., Edgar Alberto |
| spellingShingle |
Galindo Pedraza, MD., Javier Leonardo García-Herreros Ochoa, MD., FCCP., Plutarco Saavedra Rodríguez, MD., Alfredo Sánchez Morales, MD., Edgar Alberto bleomycin pulmonary toxicity pulmonary fibrosis bleomicina toxicidad pulmonar fibrosis pulmonar |
| author_facet |
Galindo Pedraza, MD., Javier Leonardo García-Herreros Ochoa, MD., FCCP., Plutarco Saavedra Rodríguez, MD., Alfredo Sánchez Morales, MD., Edgar Alberto |
| topic |
bleomycin pulmonary toxicity pulmonary fibrosis bleomicina toxicidad pulmonar fibrosis pulmonar |
| topic_facet |
bleomycin pulmonary toxicity pulmonary fibrosis bleomicina toxicidad pulmonar fibrosis pulmonar |
| topicspa_str_mv |
bleomicina toxicidad pulmonar fibrosis pulmonar |
| citationvolume |
24 |
| citationissue |
2 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/190 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
| type_coarversion |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2017-05-29 |
| date_accessioned |
2017-05-29T21:41:51Z |
| date_available |
2017-05-29T21:41:51Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/190 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v24.n2.2012.190 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v24.n2.2012.190 |
| citationstartpage |
97 |
| citationendpage |
101 |
| url2_str_mv |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/190/179 |
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1811200701635756032 |