id	metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_178
record_format	ojs
spelling	We review the activity of macrolides in chronic inflammatory airway disease, laying emphasis on their immunomodulatory and anti-inflammatory effects on the epithelial cell. We describe in detail the humoral and cellular mediators involved, as well as the interactions between these antibiotics and circulating inflammatory mediators (including processes of apoptosis and oxidation), along with the effects on epithelial defenses, actions on mucus, movement of ions, defensins, mucociliary clearance, and epithelial stabilization. Because of these mechanisms, macrolides have become an adjuvant in the management of infectious and inflammatory lung diseases. Moreno, MD., Mauricio Sáenz Morales, MD., Oscar Manrique Martínez, MD., Camilo González Acosta, MD., Francisco Vergara Vela, MD., Erika Paola Pereira Garzón, MD., Alberto Mario Miranda Jiménez, MD., Rafael macrolides immunomodulatory effects epithelial cell inflammatory airway disease inflammatory mediators macrólidos efectos inmunomodulatorios célula epitelial enfermedad inflamatoria de la vía aérea mediadores inflamatorios 23 2 Artículo de revista Journal article 2017-04-15T20:19:02Z 2017-04-15T20:19:02Z 2017-04-15 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/178 10.30789/rcneumologia.v23.n2.2011.178 https://doi.org/10.30789/rcneumologia.v23.n2.2011.178 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 40 47 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/178/167 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	We review the activity of macrolides in chronic inflammatory airway disease, laying emphasis on their immunomodulatory and anti-inflammatory effects on the epithelial cell. We describe in detail the humoral and cellular mediators involved, as well as the interactions between these antibiotics and circulating inflammatory mediators (including processes of apoptosis and oxidation), along with the effects on epithelial defenses, actions on mucus, movement of ions, defensins, mucociliary clearance, and epithelial stabilization. Because of these mechanisms, macrolides have become an adjuvant in the management of infectious and inflammatory lung diseases.
author	Moreno, MD., Mauricio Sáenz Morales, MD., Oscar Manrique Martínez, MD., Camilo González Acosta, MD., Francisco Vergara Vela, MD., Erika Paola Pereira Garzón, MD., Alberto Mario Miranda Jiménez, MD., Rafael
spellingShingle	Moreno, MD., Mauricio Sáenz Morales, MD., Oscar Manrique Martínez, MD., Camilo González Acosta, MD., Francisco Vergara Vela, MD., Erika Paola Pereira Garzón, MD., Alberto Mario Miranda Jiménez, MD., Rafael macrolides immunomodulatory effects epithelial cell inflammatory airway disease inflammatory mediators macrólidos efectos inmunomodulatorios célula epitelial enfermedad inflamatoria de la vía aérea mediadores inflamatorios
author_facet	Moreno, MD., Mauricio Sáenz Morales, MD., Oscar Manrique Martínez, MD., Camilo González Acosta, MD., Francisco Vergara Vela, MD., Erika Paola Pereira Garzón, MD., Alberto Mario Miranda Jiménez, MD., Rafael
topic	macrolides immunomodulatory effects epithelial cell inflammatory airway disease inflammatory mediators macrólidos efectos inmunomodulatorios célula epitelial enfermedad inflamatoria de la vía aérea mediadores inflamatorios
topic_facet	macrolides immunomodulatory effects epithelial cell inflammatory airway disease inflammatory mediators macrólidos efectos inmunomodulatorios célula epitelial enfermedad inflamatoria de la vía aérea mediadores inflamatorios
topicspa_str_mv	macrólidos efectos inmunomodulatorios célula epitelial enfermedad inflamatoria de la vía aérea mediadores inflamatorios
citationvolume	23
citationissue	2
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/178
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2017 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2017-04-15
date_accessioned	2017-04-15T20:19:02Z
date_available	2017-04-15T20:19:02Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/178
url_doi	https://doi.org/10.30789/rcneumologia.v23.n2.2011.178
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v23.n2.2011.178
citationstartpage	40
citationendpage	47
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/178/167
_version_	1811200700645900288

.

Código QR

Estadísticas y Métricas Alternativas

Títulos similares