Titulo:
.
Guardado en:
0121-5426
2538-9513
25
2016-12-04
Revista Colombiana de Neumología - 2016
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_121 |
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ojs |
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Pulmonary alveolar proteinosis (PAP) is a rare condition of unknown etiology that is characterized by an abnormal accumulation of lipoproteinaceus material within the alveoli. Today, three types of presentations have been identified (congenital, secondary and acquired) which have, as a common denominator, an extensive lung involvement. Primary alterations include a decrease in the clearance of surfactant or an increase in the production thereof, alterations involving genetic defects that alter the proteins that comprise the surfactant or the receptor of GM - CSF. The acquired presentation is characterized by the presence of anti – GM-CSF antibodies, thus highlighting the role of this substance in surfactant homeostasis. On this occasion, we present the case of a young female patient with lower respiratory symptoms, in whom, the low correlation between clinical appearance and extensive pulmonary parenchymal compromise is a remarkable feature. Chamorro, MD., Julia Edith Ñáñez, MD., Julián Darío Pinedo, MD., Ramiro pulmonary alveolar proteinosis pulmonary alveolar phospholipoproteinosis proteinosis alveolar pulmonar fosfolipoproteinosis alveolar pulmonar 25 2 Artículo de revista Journal article 2016-12-04T00:00:00Z 2016-12-04T00:00:00Z 2016-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/121 10.30789/rcneumologia.v25.n2.2013.121 https://doi.org/10.30789/rcneumologia.v25.n2.2013.121 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/121/115 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Pulmonary alveolar proteinosis (PAP) is a rare condition of unknown etiology that is characterized by an abnormal accumulation of lipoproteinaceus material within the alveoli. Today, three types of presentations have been identified (congenital, secondary and acquired) which have, as a common denominator, an extensive lung involvement. Primary alterations include a decrease in the clearance of surfactant or an increase in the production thereof, alterations involving genetic defects that alter the proteins that comprise the surfactant or the receptor of GM - CSF. The acquired presentation is characterized by the presence of anti – GM-CSF antibodies, thus highlighting the role of this substance in surfactant homeostasis. On this occasion, we present the case of a young female patient with lower respiratory symptoms, in whom, the low correlation between clinical appearance and extensive pulmonary parenchymal compromise is a remarkable feature.
|
| author |
Chamorro, MD., Julia Edith Ñáñez, MD., Julián Darío Pinedo, MD., Ramiro |
| spellingShingle |
Chamorro, MD., Julia Edith Ñáñez, MD., Julián Darío Pinedo, MD., Ramiro pulmonary alveolar proteinosis pulmonary alveolar phospholipoproteinosis proteinosis alveolar pulmonar fosfolipoproteinosis alveolar pulmonar |
| author_facet |
Chamorro, MD., Julia Edith Ñáñez, MD., Julián Darío Pinedo, MD., Ramiro |
| topic |
pulmonary alveolar proteinosis pulmonary alveolar phospholipoproteinosis proteinosis alveolar pulmonar fosfolipoproteinosis alveolar pulmonar |
| topic_facet |
pulmonary alveolar proteinosis pulmonary alveolar phospholipoproteinosis proteinosis alveolar pulmonar fosfolipoproteinosis alveolar pulmonar |
| topicspa_str_mv |
proteinosis alveolar pulmonar fosfolipoproteinosis alveolar pulmonar |
| citationvolume |
25 |
| citationissue |
2 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/121 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
| type_driver |
info:eu-repo/semantics/article |
| type_coar |
http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
| type_coarversion |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2016-12-04 |
| date_accessioned |
2016-12-04T00:00:00Z |
| date_available |
2016-12-04T00:00:00Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/121 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v25.n2.2013.121 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v25.n2.2013.121 |
| url2_str_mv |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/121/115 |
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1811200695805673472 |