Titulo:
.
Guardado en:
0121-5426
2538-9513
25
2016-12-04
Revista Colombiana de Neumología - 2016
info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
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metarevistapublica_asoneumocito_revistacolombianadeneumologia_28_article_120 |
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ojs |
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Pulmonary proteinosis is a rare pulmonary condition in which there is a disbalance between the production and elimination of alveolar surfactant resulting in the accumulation of lipoproteinaceous material within the alveoli. The majority of cases are caused by production of antibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) with secondary dysfunction of the alveolar macrophage and accumulation of surfactant. Nontheless there is a non-autoimmune presentation which includes the congenital and the secondary type. It has a variable course ranging from ventilatory failure to complete resolution and it predisposes to pulmonary infections. The diagnosis is based on radiologic findings in presence of positive PAS stain on the bronchoalveolar lavage. The treatment options were previously based on whole lung lavage (WLL), however other modalities of treatment have been described including Rituximab, Plasmapheresis and GM-CSF replacement. We present a case of alveolar proteinosis and review the therapeutic options for 2013. Kattah, MD., Laura Londoño, MD., Darío pulmonary alveolar proteinosis granulocyte-macrophage colony-stimulating factor proteinosis alveolar factor estimulante de colonias de macrófagos y monocitos rituximab 25 2 Artículo de revista Journal article 2016-12-04T00:00:00Z 2016-12-04T00:00:00Z 2016-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/120 10.30789/rcneumologia.v25.n2.2013.120 https://doi.org/10.30789/rcneumologia.v25.n2.2013.120 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/120/114 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc http://purl.org/redcol/resource_type/ARTREV info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication |
| institution |
ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX |
| thumbnail |
https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png |
| country_str |
Colombia |
| collection |
Revista Colombiana de Neumología |
| description_eng |
Pulmonary proteinosis is a rare pulmonary condition in which there is a disbalance between the production and elimination of alveolar surfactant resulting in the accumulation of lipoproteinaceous material within the alveoli. The majority of cases are caused by production of antibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) with secondary dysfunction of the alveolar macrophage and accumulation of surfactant. Nontheless there is a non-autoimmune presentation which includes the congenital and the secondary type. It has a variable course ranging from ventilatory failure to complete resolution and it predisposes to pulmonary infections. The diagnosis is based on radiologic findings in presence of positive PAS stain on the bronchoalveolar lavage. The treatment options were previously based on whole lung lavage (WLL), however other modalities of treatment have been described including Rituximab, Plasmapheresis and GM-CSF replacement. We present a case of alveolar proteinosis and review the therapeutic options for 2013.
|
| author |
Kattah, MD., Laura Londoño, MD., Darío |
| spellingShingle |
Kattah, MD., Laura Londoño, MD., Darío pulmonary alveolar proteinosis granulocyte-macrophage colony-stimulating factor proteinosis alveolar factor estimulante de colonias de macrófagos y monocitos rituximab |
| author_facet |
Kattah, MD., Laura Londoño, MD., Darío |
| topic |
pulmonary alveolar proteinosis granulocyte-macrophage colony-stimulating factor proteinosis alveolar factor estimulante de colonias de macrófagos y monocitos rituximab |
| topic_facet |
pulmonary alveolar proteinosis granulocyte-macrophage colony-stimulating factor proteinosis alveolar factor estimulante de colonias de macrófagos y monocitos rituximab |
| topicspa_str_mv |
proteinosis alveolar factor estimulante de colonias de macrófagos y monocitos rituximab |
| citationvolume |
25 |
| citationissue |
2 |
| publisher |
Asociación Colombiana de Neumología y Cirugía de Tórax |
| ispartofjournal |
Revista Colombiana de Neumología |
| source |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/120 |
| language |
spa |
| format |
Article |
| rights |
https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
| type_version |
info:eu-repo/semantics/publishedVersion |
| type_coarversion |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| type_content |
Text |
| publishDate |
2016-12-04 |
| date_accessioned |
2016-12-04T00:00:00Z |
| date_available |
2016-12-04T00:00:00Z |
| url |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/120 |
| url_doi |
https://doi.org/10.30789/rcneumologia.v25.n2.2013.120 |
| issn |
0121-5426 |
| eissn |
2538-9513 |
| doi |
10.30789/rcneumologia.v25.n2.2013.120 |
| url2_str_mv |
https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/120/114 |
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1811200695714447360 |