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spelling	Introduction: with regard to the clinical value of high-resolution chest scanning, it has been considered that some studies can offer very fine radiologic descriptions that often lead to additional invasive diagnostic interventions that in the end do not confirm the initial diagnostic suspicion, nor assign meaning to the described radiologic findings.Objectives: the purpose of this study is to assess the operational characteristics of chest scanning compared to a combined gold standard (biopsies, microbiologic studies, and clinical follow-up), in order to assess its diagnostic yield. It also intends to assess the need for high-resolution chest scanning in the diagnostic workup of the patient with pulmonary disease, thus assessing the percentage of additional invasive interventions that were carried out with regard to the findings of the chest scan, and that eventually had nondiagnostic results.Materials and Methods: a retrospective study was carried out by reviewing the clinical records of 250 patients who underwent high-resolution chest scanning at San Ignacio University Hospital in Bogota, Colombia, between April 2008 and April 2010. The presumptive diagnosis suggested by the images and the description of semiological findings were compared with a combined gold standard; once the final diagnosis was established by the combined gold standard, the patients were classified into etiological categories.Results: of 250 reviewed cases, it was found that 44,8% of the patients had infectious diseases, 19,6% had neoplastic diseases, 17,12% had interstitial diseases, 9,2% had other pulmonary diseases, 4% had undetermined findings, 3,2% had simultaneous infectious and interstitial disease, and 2% were normal. The sensitivity of high-resolution chest scanning for diagnosing pulmonary disease in the general population of the study was 83,3%, and its specificity was 90,9%. Positive predictive value was 99,5%, and negative predictive value was 94.09%.Conclusions: high-resolution chest scanning is a useful tool for the workup of the patient with lung disease. It is highly capable of detecting pulmonary injuries, proposing differential diagnoses, and orienting the most adequate site for biopsy. It is important to interpret the study with clinical information that permits successful diagnostic workup. Ramírez, MD., Sandra Milena Uriza, MD., MSc., Luis Felipe Londoño MD., MSc., Darío Chest CT scan sensitivity specificity high-resolution TAC de tórax sensibilidad especificidad alta resolución 25 2 Artículo de revista Journal article 2016-12-04T00:00:00Z 2016-12-04T00:00:00Z 2016-12-04 application/pdf Asociación Colombiana de Neumología y Cirugía de Tórax Revista Colombiana de Neumología 0121-5426 2538-9513 https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/117 10.30789/rcneumologia.v25.n2.2013.117 https://doi.org/10.30789/rcneumologia.v25.n2.2013.117 spa https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/117/111 info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 http://purl.org/redcol/resource_type/ART info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2 Text Publication
institution	ASOCIACION COLOMBIANA DE NEUMOLOGIA Y CIRUGIA DE TORAX
thumbnail	https://nuevo.metarevistas.org/ASOCIACIONCOLOMBIANADENEUMOLOGIAYCIRUGIADETORAX/logo.png
country_str	Colombia
collection	Revista Colombiana de Neumología
description_eng	Introduction: with regard to the clinical value of high-resolution chest scanning, it has been considered that some studies can offer very fine radiologic descriptions that often lead to additional invasive diagnostic interventions that in the end do not confirm the initial diagnostic suspicion, nor assign meaning to the described radiologic findings.Objectives: the purpose of this study is to assess the operational characteristics of chest scanning compared to a combined gold standard (biopsies, microbiologic studies, and clinical follow-up), in order to assess its diagnostic yield. It also intends to assess the need for high-resolution chest scanning in the diagnostic workup of the patient with pulmonary disease, thus assessing the percentage of additional invasive interventions that were carried out with regard to the findings of the chest scan, and that eventually had nondiagnostic results.Materials and Methods: a retrospective study was carried out by reviewing the clinical records of 250 patients who underwent high-resolution chest scanning at San Ignacio University Hospital in Bogota, Colombia, between April 2008 and April 2010. The presumptive diagnosis suggested by the images and the description of semiological findings were compared with a combined gold standard; once the final diagnosis was established by the combined gold standard, the patients were classified into etiological categories.Results: of 250 reviewed cases, it was found that 44,8% of the patients had infectious diseases, 19,6% had neoplastic diseases, 17,12% had interstitial diseases, 9,2% had other pulmonary diseases, 4% had undetermined findings, 3,2% had simultaneous infectious and interstitial disease, and 2% were normal. The sensitivity of high-resolution chest scanning for diagnosing pulmonary disease in the general population of the study was 83,3%, and its specificity was 90,9%. Positive predictive value was 99,5%, and negative predictive value was 94.09%.Conclusions: high-resolution chest scanning is a useful tool for the workup of the patient with lung disease. It is highly capable of detecting pulmonary injuries, proposing differential diagnoses, and orienting the most adequate site for biopsy. It is important to interpret the study with clinical information that permits successful diagnostic workup.
author	Ramírez, MD., Sandra Milena Uriza, MD., MSc., Luis Felipe Londoño MD., MSc., Darío
spellingShingle	Ramírez, MD., Sandra Milena Uriza, MD., MSc., Luis Felipe Londoño MD., MSc., Darío Chest CT scan sensitivity specificity high-resolution TAC de tórax sensibilidad especificidad alta resolución
author_facet	Ramírez, MD., Sandra Milena Uriza, MD., MSc., Luis Felipe Londoño MD., MSc., Darío
topic	Chest CT scan sensitivity specificity high-resolution TAC de tórax sensibilidad especificidad alta resolución
topic_facet	Chest CT scan sensitivity specificity high-resolution TAC de tórax sensibilidad especificidad alta resolución
topicspa_str_mv	TAC de tórax sensibilidad especificidad alta resolución
citationvolume	25
citationissue	2
publisher	Asociación Colombiana de Neumología y Cirugía de Tórax
ispartofjournal	Revista Colombiana de Neumología
source	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/117
language	spa
format	Article
rights	https://creativecommons.org/licenses/by-nc-sa/4.0/ Revista Colombiana de Neumología - 2016 info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
type_driver	info:eu-repo/semantics/article
type_coar	http://purl.org/coar/resource_type/c_6501
type_version	info:eu-repo/semantics/publishedVersion
type_coarversion	http://purl.org/coar/version/c_970fb48d4fbd8a85
type_content	Text
publishDate	2016-12-04
date_accessioned	2016-12-04T00:00:00Z
date_available	2016-12-04T00:00:00Z
url	https://revistas.asoneumocito.org/index.php/rcneumologia/article/view/117
url_doi	https://doi.org/10.30789/rcneumologia.v25.n2.2013.117
issn	0121-5426
eissn	2538-9513
doi	10.30789/rcneumologia.v25.n2.2013.117
url2_str_mv	https://revistas.asoneumocito.org/index.php/rcneumologia/article/download/117/111
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